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    Ppn Papilin [ Megalopta genalis ]

    Gene ID: 117228159, updated on 10-Oct-2024

    Summary

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    Gene symbol
    Ppn
    Gene description
    Papilin
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Megalopta genalis
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea; Anthophila; Halictidae; Halictinae; Augochlorini; Megalopta
    Orthologs
    fruit fly honey bee all
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    Genomic context

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    See Ppn in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    100 current USU_MGEN_1.2 (GCF_011865705.1) Unplaced Scaffold NW_022891420.1 (1274337..1636477, complement)

    NW_022891420.1Genomic Context describing neighboring genes Neighboring gene potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3-like Neighboring gene TWIK-related acid-sensitive K[+] channel 7 Neighboring gene NADH:ubiquinone oxidoreductase subunit ASHI Neighboring gene Radial spoke head protein 4a

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_022891420 Unplaced Scaffold Reference USU_MGEN_1.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Developmental Transcriptome for a Facultatively Eusocial Bee, Megalopta genalis. Jones BM, et al. G3 (Bethesda), 2015 Aug 14. PMID 26276382, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    papilin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Megalopta genalis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference USU_MGEN_1.2

    Genomic

    1. NW_022891420.1 Reference USU_MGEN_1.2

      Range
      1274337..1636477 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033483881.1 → XP_033339772.1  papilin isoform X2

      Conserved Domains (13) summary
      smart00131
      Location:2172 → 2224
      KU; BPTI/Kunitz family of serine protease inhibitors
      smart00209
      Location:62 → 113
      TSP1; Thrombospondin type 1 repeats
      cd00109
      Location:1784 → 1837
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      pfam05986
      Location:216 → 331
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam00014
      Location:1908 → 1959
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00095
      Location:2384 → 2425
      WAP; WAP-type (Whey Acidic Protein) 'four-disulfide core'
      pfam08686
      Location:2806 → 2838
      PLAC; PLAC (protease and lacunin) domain
      pfam13927
      Location:2552 → 2621
      Ig_3; Immunoglobulin domain
      pfam19030
      Location:344 → 398
      TSP1_ADAMTS; Thrombospondin type 1 domain
      cd00096
      Location:2456 → 2459
      Ig; Ig strand A' [structural motif]
      NF033609
      Location:923 → 1250
      MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
      NF033913
      Location:843 → 991
      fibronec_FbpA; LPXTG-anchored fibronectin-binding protein FbpA
      cl11960
      Location:2452 → 2527
      Ig; Immunoglobulin domain

    2. XM_033483883.1 → XP_033339774.1  papilin isoform X4

      Conserved Domains (12) summary
      smart00131
      Location:2161 → 2213
      KU; BPTI/Kunitz family of serine protease inhibitors
      smart00209
      Location:63 → 114
      TSP1; Thrombospondin type 1 repeats
      cd00109
      Location:1773 → 1826
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      pfam05986
      Location:217 → 332
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam00014
      Location:1897 → 1948
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00095
      Location:2373 → 2414
      WAP; WAP-type (Whey Acidic Protein) 'four-disulfide core'
      pfam08686
      Location:2795 → 2827
      PLAC; PLAC (protease and lacunin) domain
      pfam13927
      Location:2541 → 2610
      Ig_3; Immunoglobulin domain
      pfam19030
      Location:345 → 399
      TSP1_ADAMTS; Thrombospondin type 1 domain
      cd00096
      Location:2445 → 2448
      Ig; Ig strand A' [structural motif]
      NF033609
      Location:924 → 1233
      MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
      cl11960
      Location:2441 → 2516
      Ig; Immunoglobulin domain

    3. XM_033483886.1 → XP_033339777.1  papilin isoform X6

      Conserved Domains (13) summary
      smart00131
      Location:2113 → 2165
      KU; BPTI/Kunitz family of serine protease inhibitors
      smart00209
      Location:63 → 114
      TSP1; Thrombospondin type 1 repeats
      cd00109
      Location:1785 → 1838
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      pfam05986
      Location:217 → 332
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam00014
      Location:1849 → 1900
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00095
      Location:2325 → 2366
      WAP; WAP-type (Whey Acidic Protein) 'four-disulfide core'
      pfam08686
      Location:2747 → 2779
      PLAC; PLAC (protease and lacunin) domain
      pfam13927
      Location:2493 → 2562
      Ig_3; Immunoglobulin domain
      pfam19030
      Location:345 → 399
      TSP1_ADAMTS; Thrombospondin type 1 domain
      cd00096
      Location:2397 → 2400
      Ig; Ig strand A' [structural motif]
      NF033609
      Location:924 → 1251
      MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
      NF033913
      Location:844 → 992
      fibronec_FbpA; LPXTG-anchored fibronectin-binding protein FbpA
      cl11960
      Location:2393 → 2468
      Ig; Immunoglobulin domain

    4. XM_033483882.1 → XP_033339773.1  papilin isoform X3

      Conserved Domains (13) summary
      smart00131
      Location:2170 → 2222
      KU; BPTI/Kunitz family of serine protease inhibitors
      smart00209
      Location:63 → 114
      TSP1; Thrombospondin type 1 repeats
      cd00109
      Location:1785 → 1838
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      pfam05986
      Location:217 → 332
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam00014
      Location:1906 → 1957
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00095
      Location:2382 → 2423
      WAP; WAP-type (Whey Acidic Protein) 'four-disulfide core'
      pfam08686
      Location:2804 → 2836
      PLAC; PLAC (protease and lacunin) domain
      pfam13927
      Location:2550 → 2619
      Ig_3; Immunoglobulin domain
      pfam19030
      Location:345 → 399
      TSP1_ADAMTS; Thrombospondin type 1 domain
      cd00096
      Location:2454 → 2457
      Ig; Ig strand A' [structural motif]
      NF033609
      Location:924 → 1251
      MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
      NF033913
      Location:844 → 992
      fibronec_FbpA; LPXTG-anchored fibronectin-binding protein FbpA
      cl11960
      Location:2450 → 2525
      Ig; Immunoglobulin domain

    5. XM_033483884.1 → XP_033339775.1  papilin isoform X5

      Conserved Domains (13) summary
      smart00131
      Location:2173 → 2225
      KU; BPTI/Kunitz family of serine protease inhibitors
      smart00209
      Location:63 → 114
      TSP1; Thrombospondin type 1 repeats
      cd00109
      Location:1785 → 1838
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      pfam05986
      Location:217 → 332
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam00014
      Location:1909 → 1960
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00095
      Location:2328 → 2369
      WAP; WAP-type (Whey Acidic Protein) 'four-disulfide core'
      pfam08686
      Location:2750 → 2782
      PLAC; PLAC (protease and lacunin) domain
      pfam13927
      Location:2496 → 2565
      Ig_3; Immunoglobulin domain
      pfam19030
      Location:345 → 399
      TSP1_ADAMTS; Thrombospondin type 1 domain
      cd00096
      Location:2400 → 2403
      Ig; Ig strand A' [structural motif]
      NF033609
      Location:924 → 1251
      MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
      NF033913
      Location:844 → 992
      fibronec_FbpA; LPXTG-anchored fibronectin-binding protein FbpA
      cl11960
      Location:2396 → 2471
      Ig; Immunoglobulin domain

    6. XM_033483887.1 → XP_033339778.1  papilin isoform X7

      Conserved Domains (13) summary
      smart00131
      Location:2173 → 2225
      KU; BPTI/Kunitz family of serine protease inhibitors
      smart00209
      Location:63 → 114
      TSP1; Thrombospondin type 1 repeats
      cd00109
      Location:1785 → 1838
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      pfam05986
      Location:217 → 332
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam00014
      Location:1909 → 1960
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00095
      Location:2385 → 2426
      WAP; WAP-type (Whey Acidic Protein) 'four-disulfide core'
      pfam07679
      Location:2538 → 2629
      I-set; Immunoglobulin I-set domain
      pfam08686
      Location:2638 → 2670
      PLAC; PLAC (protease and lacunin) domain
      pfam19030
      Location:345 → 399
      TSP1_ADAMTS; Thrombospondin type 1 domain
      cd00096
      Location:2558 → 2568
      Ig; Ig strand B [structural motif]
      NF033609
      Location:924 → 1251
      MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
      NF033913
      Location:844 → 992
      fibronec_FbpA; LPXTG-anchored fibronectin-binding protein FbpA
      cl11960
      Location:2453 → 2528
      Ig; Immunoglobulin domain

    7. XM_033483880.1 → XP_033339771.1  papilin isoform X1

      Conserved Domains (13) summary
      smart00131
      Location:2173 → 2225
      KU; BPTI/Kunitz family of serine protease inhibitors
      smart00209
      Location:63 → 114
      TSP1; Thrombospondin type 1 repeats
      cd00109
      Location:1785 → 1838
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      pfam05986
      Location:217 → 332
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam00014
      Location:1909 → 1960
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam00095
      Location:2385 → 2426
      WAP; WAP-type (Whey Acidic Protein) 'four-disulfide core'
      pfam08686
      Location:2807 → 2839
      PLAC; PLAC (protease and lacunin) domain
      pfam13927
      Location:2553 → 2622
      Ig_3; Immunoglobulin domain
      pfam19030
      Location:345 → 399
      TSP1_ADAMTS; Thrombospondin type 1 domain
      cd00096
      Location:2457 → 2460
      Ig; Ig strand A' [structural motif]
      NF033609
      Location:924 → 1251
      MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
      NF033913
      Location:844 → 992
      fibronec_FbpA; LPXTG-anchored fibronectin-binding protein FbpA
      cl11960
      Location:2453 → 2528
      Ig; Immunoglobulin domain
    Nucleotide Protein
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