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    ALOX5 arachidonate 5-lipoxygenase [ Sapajus apella (tufted capuchin) ]

    Gene ID: 116545043, updated on 18-Mar-2024

    Summary

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    Gene symbol
    ALOX5
    Gene description
    arachidonate 5-lipoxygenase
    See related
    EnsemblRapid:ENSSAEG00000027558
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sapajus apella
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Cebinae; Sapajus
    Orthologs
    human mouse all
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    Genomic context

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    See ALOX5 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    100 current GSC_monkey_1.0 (GCF_009761245.1) Unplaced Scaffold NW_022437183.1 (343468..404008, complement)

    NW_022437183.1Genomic Context describing neighboring genes Neighboring gene T-complex protein 1 subunit eta-like Neighboring gene membrane associated ring-CH-type finger 8 Neighboring gene Y-box-binding protein 1 pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene olfactory receptor 13A1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_022437183 Unplaced Scaffold Reference GSC_monkey_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables arachidonate 5-lipoxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in linoleic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid oxidation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear envelope IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arachidonate 5-lipoxygenase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sapajus apella Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GSC_monkey_1.0

    Genomic

    1. NW_022437183.1 Reference GSC_monkey_1.0

      Range
      343468..404008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032271646.1 → XP_032127537.1  arachidonate 5-lipoxygenase isoform X1

      UniProtKB/TrEMBL
      A0A6J3HCE6
      Conserved Domains (2) summary
      cd01753
      Location:2 → 115
      PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
      pfam00305
      Location:227 → 665
      Lipoxygenase

    2. XM_032271645.1 → XP_032127536.1  arachidonate 5-lipoxygenase isoform X1

      UniProtKB/TrEMBL
      A0A6J3HCE6
      Related
      ENSSAEP00000028088.1, ENSSAET00000038428.1
      Conserved Domains (2) summary
      cd01753
      Location:2 → 115
      PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
      pfam00305
      Location:227 → 665
      Lipoxygenase

    3. XM_032271647.1 → XP_032127538.1  arachidonate 5-lipoxygenase isoform X2

      UniProtKB/TrEMBL
      A0A6J3HAH0
      Related
      ENSSAEP00000028085.1, ENSSAET00000038422.1
      Conserved Domains (2) summary
      cd01753
      Location:2 → 115
      PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
      pfam00305
      Location:227 → 608
      Lipoxygenase
    Nucleotide Protein
    Heading Accession and Version

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