U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    KMT2D lysine methyltransferase 2D [ Sapajus apella (tufted capuchin) ]

    Gene ID: 116562410, updated on 18-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    KMT2D
    Gene description
    lysine methyltransferase 2D
    See related
    EnsemblRapid:ENSSAEG00000003724
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sapajus apella
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Cebinae; Sapajus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See KMT2D in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    57
    Annotation release Status Assembly Chr Location
    100 current GSC_monkey_1.0 (GCF_009761245.1) Unplaced Scaffold NW_022436942.1 (27220112..27263100)

    NW_022436942.1Genomic Context describing neighboring genes Neighboring gene desert hedgehog signaling molecule Neighboring gene RHEB like 1 Neighboring gene uncharacterized LOC116562467 Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 1 Neighboring gene dendrin

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NW_022436942 Unplaced Scaffold Reference GSC_monkey_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3K4 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MLL3/4 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    histone-lysine N-methyltransferase 2D

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Sapajus apella Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GSC_monkey_1.0

    Genomic

    1. NW_022436942.1 Reference GSC_monkey_1.0

      Range
      27220112..27263100
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032294718.1 → XP_032150609.1  histone-lysine N-methyltransferase 2D isoform X12

      UniProtKB/TrEMBL
      A0A6J3J8Z4
      Related
      ENSSAEP00000003820.1, ENSSAET00000005221.1
      Conserved Domains (14) summary
      TIGR01645
      Location:4297 → 4493
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:2039 → 2090
      HMG; high mobility group
      smart00542
      Location:5265 → 5352
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:2125 → 2564
      PHA03247; large tegument protein UL36; Provisional
      cd15509
      Location:228 → 273
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15513
      Location:1447 → 1493
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:1396 → 1446
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:1524 → 1574
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15695
      Location:134 → 217
      ePHD1_KMT2D; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:5057 → 5163
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:4020 → 4374
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:5407 → 5561
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:5206 → 5257
      FYRN; F/Y-rich N-terminus
      cl22851
      Location:275 → 320
      PHD_SF; PHD finger superfamily

    2. XM_032294668.1 → XP_032150559.1  histone-lysine N-methyltransferase 2D isoform X6

      UniProtKB/TrEMBL
      A0A6J3J8U2
      Conserved Domains (11) summary
      TIGR01645
      Location:3353 → 3549
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1095 → 1146
      HMG; high mobility group
      smart00542
      Location:4321 → 4408
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1181 → 1620
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:500 → 546
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:449 → 499
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:577 → 627
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4113 → 4219
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3076 → 3430
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4479 → 4633
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4262 → 4313
      FYRN; F/Y-rich N-terminus

    3. XM_032294674.1 → XP_032150565.1  histone-lysine N-methyltransferase 2D isoform X7

      UniProtKB/TrEMBL
      A0A6J3J814
      Conserved Domains (11) summary
      TIGR01645
      Location:3350 → 3546
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1092 → 1143
      HMG; high mobility group
      smart00542
      Location:4318 → 4405
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1178 → 1617
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:500 → 546
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:449 → 499
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:577 → 627
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4110 → 4216
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3073 → 3427
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4476 → 4630
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4259 → 4310
      FYRN; F/Y-rich N-terminus

    4. XM_032294679.1 → XP_032150570.1  histone-lysine N-methyltransferase 2D isoform X8

      UniProtKB/TrEMBL
      A0A6J3J820
      Conserved Domains (11) summary
      TIGR01645
      Location:3349 → 3545
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1091 → 1142
      HMG; high mobility group
      smart00542
      Location:4317 → 4404
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1177 → 1616
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:499 → 545
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:448 → 498
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:576 → 626
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4109 → 4215
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3072 → 3426
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4475 → 4629
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4258 → 4309
      FYRN; F/Y-rich N-terminus

    5. XM_032294697.1 → XP_032150588.1  histone-lysine N-methyltransferase 2D isoform X10

      UniProtKB/TrEMBL
      A0A6J3J7T0
      Conserved Domains (11) summary
      TIGR01645
      Location:3349 → 3545
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1091 → 1142
      HMG; high mobility group
      smart00542
      Location:4317 → 4404
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1177 → 1616
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:499 → 545
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:448 → 498
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:576 → 626
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4109 → 4215
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3072 → 3426
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4459 → 4613
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4258 → 4309
      FYRN; F/Y-rich N-terminus

    6. XM_032294641.1 → XP_032150532.1  histone-lysine N-methyltransferase 2D isoform X3

      UniProtKB/TrEMBL
      A0A6J3J6M2
      Conserved Domains (11) summary
      TIGR01645
      Location:3353 → 3549
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1095 → 1146
      HMG; high mobility group
      smart00542
      Location:4321 → 4408
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1181 → 1620
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:500 → 546
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:449 → 499
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:577 → 627
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4113 → 4219
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3076 → 3430
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4463 → 4617
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4262 → 4313
      FYRN; F/Y-rich N-terminus

    7. XM_032294652.1 → XP_032150543.1  histone-lysine N-methyltransferase 2D isoform X4

      UniProtKB/TrEMBL
      A0A6J3J7N1
      Conserved Domains (11) summary
      TIGR01645
      Location:3353 → 3549
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1095 → 1146
      HMG; high mobility group
      smart00542
      Location:4299 → 4386
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1181 → 1620
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:500 → 546
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:449 → 499
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:577 → 627
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4091 → 4197
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3076 → 3430
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4457 → 4611
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4240 → 4291
      FYRN; F/Y-rich N-terminus

    8. XM_032294662.1 → XP_032150553.1  histone-lysine N-methyltransferase 2D isoform X5

      UniProtKB/TrEMBL
      A0A6J3J7P3
      Conserved Domains (11) summary
      TIGR01645
      Location:3353 → 3549
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1095 → 1146
      HMG; high mobility group
      smart00542
      Location:4298 → 4385
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1181 → 1620
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:500 → 546
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:449 → 499
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:577 → 627
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4090 → 4196
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3076 → 3430
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4456 → 4610
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4239 → 4290
      FYRN; F/Y-rich N-terminus

    9. XM_032294707.1 → XP_032150598.1  histone-lysine N-methyltransferase 2D isoform X11

      UniProtKB/TrEMBL
      A0A6J3J7U3
      Conserved Domains (11) summary
      TIGR01645
      Location:3177 → 3373
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1095 → 1146
      HMG; high mobility group
      smart00542
      Location:4145 → 4232
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1181 → 1620
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:500 → 546
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:449 → 499
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:577 → 627
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:3937 → 4043
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:2900 → 3254
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4303 → 4457
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4086 → 4137
      FYRN; F/Y-rich N-terminus

    10. XM_032294689.1 → XP_032150580.1  histone-lysine N-methyltransferase 2D isoform X9

      UniProtKB/TrEMBL
      A0A6J3J828
      Conserved Domains (11) summary
      TIGR01645
      Location:3322 → 3518
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1095 → 1146
      HMG; high mobility group
      smart00542
      Location:4290 → 4377
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1132 → 1589
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:500 → 546
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:449 → 499
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:577 → 627
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4082 → 4188
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3045 → 3399
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4448 → 4602
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4231 → 4282
      FYRN; F/Y-rich N-terminus

    11. XM_032294634.1 → XP_032150525.1  histone-lysine N-methyltransferase 2D isoform X2

      UniProtKB/TrEMBL
      A0A6J3J7X6
      Conserved Domains (11) summary
      TIGR01645
      Location:3346 → 3542
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1088 → 1139
      HMG; high mobility group
      smart00542
      Location:4314 → 4401
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1174 → 1613
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:500 → 546
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:449 → 499
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:577 → 627
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4106 → 4212
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3069 → 3423
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4472 → 4626
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4255 → 4306
      FYRN; F/Y-rich N-terminus

    12. XM_032294625.1 → XP_032150516.1  histone-lysine N-methyltransferase 2D isoform X1

      UniProtKB/TrEMBL
      A0A6J3J6M1
      Conserved Domains (11) summary
      TIGR01645
      Location:3352 → 3548
      half-pint; poly-U binding splicing factor, half-pint family
      smart00398
      Location:1094 → 1145
      HMG; high mobility group
      smart00542
      Location:4320 → 4407
      FYRC; FY-rich domain, C-terminal region
      PHA03247
      Location:1180 → 1619
      PHA03247; large tegument protein UL36; Provisional
      cd15513
      Location:499 → 545
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15597
      Location:448 → 498
      PHD3_KMT2D; PHD finger 3 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15601
      Location:576 → 626
      PHD5_KMT2D; PHD finger 5 found in Histone-lysine N-methyltransferase 2D (KMT2D)
      cd15698
      Location:4112 → 4218
      ePHD2_KMT2D; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2D (KMT2D)
      pfam09606
      Location:3075 → 3429
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cd19209
      Location:4478 → 4632
      SET_KMT2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2D (KMT2D) and similar proteins
      pfam05964
      Location:4261 → 4312
      FYRN; F/Y-rich N-terminus
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.