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    SH3PXD2A SH3 and PX domains 2A [ Sarcophilus harrisii (Tasmanian devil) ]

    Gene ID: 100914239, updated on 8-Mar-2024

    Summary

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    Gene symbol
    SH3PXD2A
    Gene description
    SH3 and PX domains 2A
    See related
    Ensembl:ENSSHAG00000017659
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sarcophilus harrisii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
    Orthologs
    human mouse all
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    Genomic context

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    See SH3PXD2A in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current mSarHar1.11 (GCF_902635505.1) 2 NC_045427.1 (559584437..559904121, complement)
    102 previous assembly Devil_ref v7.0 (GCF_000189315.1) 1 Unlocalized Scaffold NW_003816475.1 (2881681..3200071)

    Chromosome 2 - NC_045427.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116421885 Neighboring gene neuralized E3 ubiquitin protein ligase 1 Neighboring gene uncharacterized LOC116421886 Neighboring gene STN1 subunit of CST complex Neighboring gene STE20 like kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables superoxide-generating NADPH oxidase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in superoxide anion generation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SH3 and PX domain-containing protein 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mSarHar1.11 Primary Assembly

    Genomic

    1. NC_045427.1 Reference mSarHar1.11 Primary Assembly

      Range
      559584437..559904121 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031955791.1 → XP_031811651.1  SH3 and PX domain-containing protein 2A isoform X3

      UniProtKB/TrEMBL
      A0A7N4PA02, A0A7N4V3V1
      Related
      ENSSHAP00000034364.1, ENSSHAT00000024613.1

    2. XM_031955789.1 → XP_031811649.1  SH3 and PX domain-containing protein 2A isoform X2

      UniProtKB/TrEMBL
      A0A7N4V3V1, G3WZG6
      Related
      ENSSHAP00000020821.1, ENSSHAT00000020988.2
      Conserved Domains (6) summary
      cd06888
      Location:6 → 124
      PX_FISH; The phosphoinositide binding Phox Homology domain of Five SH protein
      cd12019
      Location:828 → 880
      SH3_Tks5_4; Fourth Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12020
      Location:1062 → 1118
      SH3_Tks5_5; Fifth (C-terminal) Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12074
      Location:155 → 207
      SH3_Tks5_1; First Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12077
      Location:254 → 307
      SH3_Tks5_2; Second Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12079
      Location:436 → 489
      SH3_Tks5_3; Third Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains

    3. XM_023496115.2 → XP_023351883.1  SH3 and PX domain-containing protein 2A isoform X1

      UniProtKB/TrEMBL
      A0A7N4PDP9, A0A7N4V3V1
      Related
      ENSSHAP00000036254.1, ENSSHAT00000045519.1
      Conserved Domains (7) summary
      cd06888
      Location:6 → 124
      PX_FISH; The phosphoinositide binding Phox Homology domain of Five SH protein
      cd12019
      Location:843 → 895
      SH3_Tks5_4; Fourth Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12020
      Location:1077 → 1133
      SH3_Tks5_5; Fifth (C-terminal) Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12074
      Location:170 → 222
      SH3_Tks5_1; First Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12077
      Location:269 → 322
      SH3_Tks5_2; Second Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12079
      Location:451 → 504
      SH3_Tks5_3; Third Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      TIGR04211
      Location:859 → 943
      SH3_and_anchor; SH3 domain protein

    4. XM_031955792.1 → XP_031811652.1  SH3 and PX domain-containing protein 2A isoform X4

      UniProtKB/TrEMBL
      A0A7N4NTD5
      Conserved Domains (5) summary
      cd12019
      Location:718 → 770
      SH3_Tks5_4; Fourth Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12020
      Location:952 → 1008
      SH3_Tks5_5; Fifth (C-terminal) Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12074
      Location:45 → 97
      SH3_Tks5_1; First Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12077
      Location:144 → 197
      SH3_Tks5_2; Second Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cl17036
      Location:326 → 379
      SH3; Src Homology 3 domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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