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    bbln-1 Bublin coiled-coil protein [ Caenorhabditis elegans ]

    Gene ID: 180605, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bbln-1
    Official Full Name
    Bublin coiled-coil protein
    Primary source
    WormBase:WBGene00015791
    Locus tag
    CELE_C15C7.5
    See related
    AllianceGenome:WB:WBGene00015791
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables molecular adaptor activity. Involved in intermediate filament bundle assembly. Located in cell junction; intermediate filament; and subapical part of cell. Is expressed in head neurons; intestine; and pharyngeal muscle cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See bbln-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    3
    Sequence:
    Chromosome: X; NC_003284.9 (3151148..3152461, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Small EDRK-rich factor-like N-terminal domain-containing protein Neighboring gene Activin_recp domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BBLN-1 is essential for intermediate filament organization and apical membrane morphology. Remmelzwaal S, et al. Curr Biol, 2021 Jun 7. PMID 33857431
    2. Intermediate filament network perturbation in the C. elegans intestine causes systemic dysfunctions. Geisler F, et al. Elife, 2023 Jun 7. PMID 37283438, Free PMC Article
    3. The Caenorhabditis elegans heterochronic regulator LIN-14 is a novel transcription factor that controls the developmental timing of transcription from the insulin/insulin-like growth factor gene ins-33 by direct DNA binding. Hristova M, et al. Mol Cell Biol, 2005 Dec. PMID 16314527, Free PMC Article
    4. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular adaptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intermediate filament bundle assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in anchoring junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell junction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intermediate filament IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in subapical part of cell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Bublin coiled-coil protein
    NP_508542.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3151148..3152461 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076141.7 → NP_508542.1  Bublin coiled-coil protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508542.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18012
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q18012.1

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