ZK795.3 Brix domain-containing protein ZK795.3 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ZK795.3
Official Full Name: Brix domain-containing protein ZK795.3
Primary source: WormBase:WBGene00014083
Locus tag: CELE_ZK795.3
See related: AllianceGenome:WB:WBGene00014083
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing. Predicted to be part of Mpp10 complex and small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including P6.pa; P6.paa; enteric muscle; excretory cell; and reproductive system. Orthologous to human IMP4 (IMP U3 small nucleolar ribonucleoprotein 4). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ZK795.3 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 5

Sequence:: Chromosome: IV; NC_003282.8 (12559365..12560672)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

ZK795.3 (e-PCR)
- UniSTS:310549

ZK795.2 (e-PCR)
- UniSTS:316332

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables rRNA binding	IEA Inferred from Electronic Annotation more info
enables rRNA primary transcript binding	IEA Inferred from Electronic Annotation more info
enables snoRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in rRNA processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in rRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Mpp10 complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
part_of small-subunit processome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Brix domain-containing protein ZK795.3

NP_502404.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

12559365..12560672

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_070003.6 → NP_502404.1 Brix domain-containing protein ZK795.3 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_502404.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O62518

Conserved Domains (1) summary

smart00879
Location:81 → 248

Brix; The Brix domain is found in a number of eukaryotic proteins