F54D1.1 KH domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F54D1.1
Official Full Name: KH domain-containing protein
Primary source: WormBase:WBGene00010046
Locus tag: CELE_F54D1.1
See related: AllianceGenome:WB:WBGene00010046
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable mRNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See F54D1.1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 5

Sequence:: Chromosome: IV; NC_003282.8 (11261835..11263075)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C05C12.5 (e-PCR)
- UniSTS:315409

F54D1.1 (e-PCR)
- UniSTS:311772

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: KH domain-containing protein

NP_502114.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

11261835..11263075

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_069713.2 → NP_502114.1 KH domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_502114.1

Status: REVIEWED

UniProtKB/TrEMBL

Q20763

Conserved Domains (1) summary

cd02395
Location:133 → 257

SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...