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    LOC574871 protein scribble homolog [ Strongylocentrotus purpuratus (purple sea urchin) ]

    Gene ID: 574871, updated on 14-Dec-2023

    Summary

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    Gene symbol
    LOC574871
    Gene description
    protein scribble homolog
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Strongylocentrotus purpuratus
    Lineage
    Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus
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    Genomic context

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    See LOC574871 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    43
    Annotation release Status Assembly Chr Location
    102 current Spur_5.0 (GCF_000002235.5) Unplaced Scaffold NW_022145613.1 (27014448..27135503, complement)
    Build 3.1 previous assembly Spur_3.1 (GCF_000002235.3) Unplaced Scaffold NW_003577127.1 (347125..401390, complement)

    NW_022145613.1Genomic Context describing neighboring genes Neighboring gene MFS-type transporter SLC18B1 Neighboring gene valosin containing protein lysine methyltransferase Neighboring gene solute carrier family 17 member 5 Neighboring gene uncharacterized LOC575016

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis. Tu Q, et al. Genome Res, 2012 Oct. PMID 22709795, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neurotransmitter receptor transport postsynaptic membrane to endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein scribble homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Strongylocentrotus purpuratus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Spur_5.0 Primary Assembly

    Genomic

    1. NW_022145613.1 Reference Spur_5.0 Primary Assembly

      Range
      27014448..27135503 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030974591.1 → XP_030830451.1  protein scribble homolog isoform X5

      UniProtKB/TrEMBL
      A0A7M7N355
      Conserved Domains (7) summary
      smart00228
      Location:791 → 879
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:648 → 725
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1421 → 1661
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1547 → 1651
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    2. XM_030974594.1 → XP_030830454.1  protein scribble homolog isoform X8

      UniProtKB/TrEMBL
      A0A7M7N4J0
      Conserved Domains (6) summary
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1401 → 1641
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1527 → 1631
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    3. XM_030974597.1 → XP_030830457.1  protein scribble homolog isoform X11

      UniProtKB/TrEMBL
      A0A7M7N304
      Conserved Domains (7) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1341 → 1581
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1467 → 1571
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    4. XM_030974598.1 → XP_030830458.1  protein scribble homolog isoform X12

      UniProtKB/TrEMBL
      A0A7M7STQ3
      Conserved Domains (7) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1340 → 1580
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1466 → 1570
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    5. XM_030974593.1 → XP_030830453.1  protein scribble homolog isoform X7

      UniProtKB/TrEMBL
      A0A7M7N387
      Conserved Domains (7) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1416 → 1656
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1542 → 1646
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    6. XM_030974592.1 → XP_030830452.1  protein scribble homolog isoform X6

      UniProtKB/TrEMBL
      A0A7M7N356
      Conserved Domains (7) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1420 → 1660
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1546 → 1650
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    7. XM_030974596.1 → XP_030830456.1  protein scribble homolog isoform X10

      UniProtKB/TrEMBL
      A0A7M7STK3
      Conserved Domains (7) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1359 → 1599
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1485 → 1589
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    8. XM_030974589.1 → XP_030830449.1  protein scribble homolog isoform X3

      UniProtKB/TrEMBL
      A0A7M7N4N9
      Conserved Domains (7) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1435 → 1675
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1561 → 1665
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    9. XM_030974595.1 → XP_030830455.1  protein scribble homolog isoform X9

      UniProtKB/TrEMBL
      A0A7M7N5Q7
      Conserved Domains (7) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1363 → 1603
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1489 → 1593
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    10. XM_030974590.1 → XP_030830450.1  protein scribble homolog isoform X4

      UniProtKB/TrEMBL
      A0A7M7N305
      Conserved Domains (7) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1439 → 1679
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1565 → 1669
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    11. XM_030974587.1 → XP_030830447.1  protein scribble homolog isoform X2

      UniProtKB/TrEMBL
      A0A7M7N3J3
      Conserved Domains (7) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1439 → 1679
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1565 → 1669
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    12. XM_030974586.1 → XP_030830446.1  protein scribble homolog isoform X1

      UniProtKB/TrEMBL
      A0A7M7STQ1
      Conserved Domains (7) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      PTZ00441
      Location:1439 → 1679
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam02389
      Location:1565 → 1669
      Cornifin; Cornifin (SPRR) family
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    13. XM_030974603.1 → XP_030830463.1  protein scribble homolog isoform X17

      UniProtKB/TrEMBL
      A0A7M7N365
      Conserved Domains (5) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    14. XM_030974602.1 → XP_030830462.1  protein scribble homolog isoform X16

      UniProtKB/TrEMBL
      A0A7M7N313
      Conserved Domains (5) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    15. XM_030974601.1 → XP_030830461.1  protein scribble homolog isoform X15

      UniProtKB/TrEMBL
      A0A7M7N4P8

    16. XM_030974600.1 → XP_030830460.1  protein scribble homolog isoform X14

      UniProtKB/TrEMBL
      A0A7M7N2V0
      Conserved Domains (5) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    17. XM_030974605.1 → XP_030830465.1  protein scribble homolog isoform X18

      UniProtKB/TrEMBL
      A0A7M7N398
      Conserved Domains (5) summary
      smart00228
      Location:809 → 897
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      COG4886
      Location:81 → 404
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:666 → 743
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:15 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:38 → 95
      LRR_8; Leucine rich repeat

    18. XM_030974599.1 → XP_030830459.1  protein scribble homolog isoform X13

      UniProtKB/TrEMBL
      A0A7M7N3K6
    Nucleotide Protein
    Heading Accession and Version

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