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    MLPH melanophilin [ Gopherus evgoodei (Goodes thornscrub tortoise) ]

    Gene ID: 115659891, updated on 17-Mar-2024

    Summary

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    Gene symbol
    MLPH
    Gene description
    melanophilin
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gopherus evgoodei
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Testudinidae; Gopherus
    Orthologs
    human mouse all
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    Genomic context

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    See MLPH in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    100 current rGopEvg1_v1.p (GCF_007399415.2) 11 NC_044332.1 (6494435..6583425)

    Chromosome 11 - NC_044332.1Genomic Context describing neighboring genes Neighboring gene COP9 signalosome subunit 8 Neighboring gene uncharacterized LOC115659759 Neighboring gene collagen type VI alpha 3 chain Neighboring gene prolactin releasing hormone Neighboring gene RAB17, member RAS oncogene family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_044332.1 Chromosome 11 Reference rGopEvg1_v1.p Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables myosin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cortical actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    melanophilin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gopherus evgoodei Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference rGopEvg1_v1.p Primary Assembly

    Genomic

    1. NC_044332.1 Reference rGopEvg1_v1.p Primary Assembly

      Range
      6494435..6583425
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030580637.1 → XP_030436497.1  melanophilin isoform X4

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:474 → 606
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus

    2. XM_030580636.1 → XP_030436496.1  melanophilin isoform X3

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:446 → 609
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus

    3. XM_030580638.1 → XP_030436498.1  melanophilin isoform X5

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:431 → 594
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus

    4. XM_030580631.1 → XP_030436491.1  melanophilin isoform X1

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:474 → 637
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus

    5. XM_030580642.1 → XP_030436502.1  melanophilin isoform X9

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:456 → 588
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus

    6. XM_030580639.1 → XP_030436499.1  melanophilin isoform X6

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:428 → 591
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus

    7. XM_030580641.1 → XP_030436501.1  melanophilin isoform X8

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:385 → 548
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus

    8. XM_030580634.1 → XP_030436494.1  melanophilin isoform X2

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:456 → 619
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus

    9. XM_030580640.1 → XP_030436500.1  melanophilin isoform X7

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:413 → 576
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus

    10. XM_030580632.1 → XP_030436492.1  melanophilin isoform X1

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:474 → 637
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus

    11. XM_030580633.1 → XP_030436493.1  melanophilin isoform X1

      Conserved Domains (2) summary
      pfam02318
      Location:8 → 125
      FYVE_2; FYVE-type zinc finger
      pfam04698
      Location:474 → 637
      Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus
    Nucleotide Protein
    Heading Accession and Version

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