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    UBR2 ubiquitin protein ligase E3 component n-recognin 2 [ Suricata suricatta (meerkat) ]

    Gene ID: 115295415, updated on 17-Mar-2024

    Summary

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    Gene symbol
    UBR2
    Gene description
    ubiquitin protein ligase E3 component n-recognin 2
    See related
    Ensembl:ENSSSUG00005001136
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Suricata suricatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Herpestidae; Suricata
    Orthologs
    human mouse all
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    Genomic context

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    See UBR2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    100 current meerkat_22Aug2017_6uvM2_HiC (GCF_006229205.1) 7 NC_043706.1 (39410108..39536570)

    Chromosome 7 - NC_043706.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene mitochondrial ribosomal protein S10 Neighboring gene transcriptional regulating factor 1 Neighboring gene peripherin 2 Neighboring gene tubulin folding cofactor C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_043706.1 Chromosome 7 Reference meerkat_22Aug2017_6uvM2_HiC

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process via the N-end rule pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase UBR2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Suricata suricatta Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference meerkat_22Aug2017_6uvM2_HiC

    Genomic

    1. NC_043706.1 Reference meerkat_22Aug2017_6uvM2_HiC

      Range
      39410108..39536570
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029943301.1 → XP_029799161.1  E3 ubiquitin-protein ligase UBR2 isoform X6

      Conserved Domains (2) summary
      pfam02207
      Location:98 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:222 → 300
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    2. XM_029943299.1 → XP_029799159.1  E3 ubiquitin-protein ligase UBR2 isoform X5

    3. XM_029943298.1 → XP_029799158.1  E3 ubiquitin-protein ligase UBR2 isoform X4

      Conserved Domains (3) summary
      pfam02207
      Location:98 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:222 → 300
      ClpS; ATP-dependent Clp protease adaptor protein ClpS
      cl17238
      Location:1107 → 1179
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    4. XM_029943296.1 → XP_029799156.1  E3 ubiquitin-protein ligase UBR2 isoform X2

      UniProtKB/TrEMBL
      A0A673SS33, A0A673SYR7
      Related
      ENSSSUP00005002363.1, ENSSSUT00005002758.1
      Conserved Domains (3) summary
      cd16686
      Location:1107 → 1222
      RING-H2_UBR2; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-2 (UBR2) and similar proteins
      pfam02207
      Location:98 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:222 → 300
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    5. XM_029943295.1 → XP_029799155.1  E3 ubiquitin-protein ligase UBR2 isoform X1

      UniProtKB/TrEMBL
      A0A673SYR7, A0A673SZL6
      Related
      ENSSSUP00005002259.1, ENSSSUT00005002638.1
      Conserved Domains (3) summary
      cd16686
      Location:1107 → 1222
      RING-H2_UBR2; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-2 (UBR2) and similar proteins
      pfam02207
      Location:98 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:222 → 300
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    6. XM_029943297.1 → XP_029799157.1  E3 ubiquitin-protein ligase UBR2 isoform X3

      UniProtKB/TrEMBL
      A0A673SYR7
    Nucleotide Protein
    Heading Accession and Version

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