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    CAMK2D calcium/calmodulin dependent protein kinase II delta [ Homo sapiens (human) ]

    Gene ID: 817, updated on 10-Dec-2024

    Summary

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    Official Symbol
    CAMK2Dprovided by HGNC
    Official Full Name
    calcium/calmodulin dependent protein kinase II deltaprovided by HGNC
    Primary source
    HGNC:HGNC:1462
    See related
    Ensembl:ENSG00000145349 MIM:607708; AllianceGenome:HGNC:1462
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CAMKD
    Summary
    The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.[provided by RefSeq, Nov 2008]
    Expression
    Ubiquitous expression in heart (RPKM 23.1), brain (RPKM 14.9) and 24 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See CAMK2D in Genome Data Viewer
    Location:
    4q26
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (113451032..113761738, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (116759793..117070469, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (114372188..114682894, complement)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377374 Neighboring gene RNA, 7SL, cytoplasmic 184, pseudogene Neighboring gene RNA, U1 small nuclear 138, pseudogene Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr4:114373445-114373992 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15644 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15645 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_72235 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:114481688-114482887 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_72247 Neighboring gene Sharpr-MPRA regulatory region 13729 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15646 Neighboring gene Sharpr-MPRA regulatory region 15168 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr4:114566848-114567352 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21838 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15647 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:114683084-114683622 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:114683623-114684161 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15648 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21839 Neighboring gene uncharacterized LOC105377375 Neighboring gene NANOG hESC enhancer GRCh37_chr4:114805704-114806205 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr4:114839688-114840887 Neighboring gene arylsulfatase family member J

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium. Hoch B, et al. Circ Res, 1999 Apr 2. PMID 10189359
    2. Structure and regulation of calcium/calmodulin-dependent protein kinases. Soderling TR, et al. Chem Rev, 2001 Aug. PMID 11749376
    3. Genome-wide association study of survival in early-stage non-small cell lung cancer. Tang S, et al. Ann Surg Oncol, 2015 Feb. PMID 25145502
    4. Inhibition of elevated Ca2+/calmodulin-dependent protein kinase II improves contractility in human failing myocardium. Sossalla S, et al. Circ Res, 2010 Oct 29. PMID 20814023
    5. Cardiac ryanodine receptor phosphorylation by CaM Kinase II: keeping the balance right. Currie S. Front Biosci (Landmark Ed), 2009 Jun 1. PMID 19482609

    See all (166) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Role of CAMK2D in neurodevelopment and associated conditions.
      Title: Role of CAMK2D in neurodevelopment and associated conditions.
    2. CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma.
      Title: CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma.
    3. TRPM1 promotes tumor progression in acral melanoma by activating the Ca[2+]/CaMKIIdelta/AKT pathway.
      Title: TRPM1 promotes tumor progression in acral melanoma by activating the Ca(2+)/CaMKIIδ/AKT pathway.
    4. miR-145-5p affects autophagy by targeting CaMKIIdelta in atherosclerosis.
      Title: miR-145-5p affects autophagy by targeting CaMKIIδ in atherosclerosis.
    5. Sphingosine kinase 1 regulates HMGB1 translocation by directly interacting with calcium/calmodulin protein kinase II-delta in sepsis-associated liver injury.
      Title: Sphingosine kinase 1 regulates HMGB1 translocation by directly interacting with calcium/calmodulin protein kinase II-δ in sepsis-associated liver injury.
    6. This study provides new evidence supporting direct interaction between CaMKIIdelta and IKKbeta in pro-inflammatory signalling in cardiac fibroblasts and could represent a feature that may be exploited for therapeutic benefit.
      Title: CaMKIIδ interacts directly with IKKβ and modulates NF-κB signalling in adult cardiac fibroblasts.
    7. JNK2 activation up-regulates CaMKIIdelta expression in the aged atrium and may promote the occurrence of cardiac arrhythmias.
      Title: Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium.
    8. CKIalpha-mediated NS5A S235 phosphorylation is critical for HCV replication. CaMKII gamma and delta may have negative roles in the HCV life cycle.
      Title: Phosphorylation of Serine 235 of the Hepatitis C Virus Non-Structural Protein NS5A by Multiple Kinases.
    9. TGFbeta elevated the expression of CamK IIbeta and CamK IIdelta, while siRNA silencing of those two subtypes significantly reduced TGFbeta-mediated expression of collagen A1 and fibronectin 1.
      Title: Ca(2+)/calmodulin-dependent protein kinase IIβ and IIδ mediate TGFβ-induced transduction of fibronectin and collagen in human pulmonary fibroblasts.
    10. CEACAM1 is able to maintain the active transcription of ID4 by an epigenetic mechanism involving HDAC4 and CaMK2D, and the same kinase enables lumen formation by CEACAM1
      Title: Induction of Lumen Formation in a Three-dimensional Model of Mammary Morphogenesis by Transcriptional Regulator ID4: ROLE OF CaMK2D IN THE EPIGENETIC REGULATION OF ID4 GENE EXPRESSION.
    Submit: New GeneRIF Correction See all GeneRIFs (32)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
    EBI GWAS Catalog
    Genome-wide Association Study of Survival in Early-stage Non-Small Cell Lung Cancer.
    EBI GWAS Catalog
    White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC44911, DKFZp686I2288, DKFZp686G23119

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium/calmodulin-dependent protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium/calmodulin-dependent protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables calmodulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calmodulin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sodium channel inhibitor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables titin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transmembrane transporter binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transmembrane transporter binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cardiac muscle cell contraction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in cellular response to calcium ion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in endoplasmic reticulum calcium ion homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in negative regulation of sodium ion transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of sodium ion transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of cardiac muscle cell apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of cardiac muscle hypertrophy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein autophosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of calcium ion transmembrane transport via high voltage-gated calcium channel ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of cardiac muscle cell action potential ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of cardiac muscle cell action potential involved in regulation of contraction IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of cell communication by electrical coupling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of cell communication by electrical coupling involved in cardiac conduction IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in regulation of cell growth NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of cellular localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of heart contraction TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of heart rate by cardiac conduction IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in regulation of membrane depolarization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of neuronal synaptic plasticity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of protein localization to plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of relaxation of cardiac muscle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of ryanodine-sensitive calcium-release channel activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of the force of heart contraction TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in relaxation of cardiac muscle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of calcium- and calmodulin-dependent protein kinase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in endocytic vesicle membrane TAS
    Traceable Author Statement
    more info
    		  
    located_in membrane HDA PubMed 
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    is_active_in postsynaptic density IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in sarcolemma IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in sarcoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    calcium/calmodulin-dependent protein kinase type II subunit delta
    Names
    CaM kinase II delta subunit
    CaM-kinase II delta chain
    CaMK-II delta subunit
    calcium/calmodulin-dependent protein kinase (CaM kinase) II delta
    calcium/calmodulin-dependent protein kinase type II delta chain
    NP_001212.2
    NP_001308495.1
    NP_001308496.1
    NP_001308497.1
    NP_001308498.1
    NP_001308499.1
    NP_001308500.1
    NP_001308501.1
    NP_001308502.1
    NP_001308503.1
    NP_001308504.1
    NP_001308505.1
    NP_001308506.1
    NP_001308507.1
    NP_001308508.1
    NP_001308509.1
    NP_001308510.1
    NP_001308511.1
    NP_001308512.1
    NP_001308513.1
    NP_001308514.1
    NP_001308515.1
    NP_001308516.1
    NP_001308517.1
    NP_001308518.1
    NP_001308519.1
    NP_001308520.1
    NP_001308521.1
    NP_001383893.1
    NP_001383894.1
    NP_001383895.1
    NP_001383896.1
    NP_001386784.1
    NP_001386785.1
    NP_001386786.1
    NP_001386787.1
    NP_001386788.1
    NP_001386789.1
    NP_001386790.1
    NP_001386791.1
    NP_001386792.1
    NP_001386793.1
    NP_001386794.1
    NP_742112.1
    NP_742113.1
    NP_742125.1
    NP_742126.1
    NP_742127.1
    XP_011530594.1
    XP_011530597.1
    XP_016864163.1
    XP_047272176.1
    XP_047272177.1
    XP_047272178.1
    XP_047272179.1
    XP_054206906.1
    XP_054206907.1
    XP_054206908.1
    XP_054206909.1
    XP_054206910.1
    XP_054206911.1
    XP_054206912.1
    XP_054206913.1
    XP_054206914.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001221.4 → NP_001212.2  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 3

      See identical proteins and their annotated locations for NP_001212.2

      Status: REVIEWED

      Source sequence(s)
      AB209288, AC093900, AI057019, AK055642, CF551834, DA113081
      Consensus CDS
      CCDS3703.1
      UniProtKB/Swiss-Prot
      A8MVS8, Q13557, Q52PK4, Q59G21, Q8N553, Q9UGH6, Q9UQE9
      UniProtKB/TrEMBL
      B7Z2B0
      Related
      ENSP00000339740.5, ENST00000342666.9
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:346 → 473
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    2. NM_001321566.2 → NP_001308495.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93607.1
      UniProtKB/TrEMBL
      B7Z2B0
      Related
      ENSP00000514099.1, ENST00000699047.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:360 → 487
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    3. NM_001321567.2 → NP_001308496.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS82948.1
      UniProtKB/TrEMBL
      A0A8V8TND4, E9PBG7
      Related
      ENSP00000424245.1, ENST00000505990.5
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:380 → 507
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    4. NM_001321568.2 → NP_001308497.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:371 → 498
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    5. NM_001321569.2 → NP_001308498.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 9

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      B7Z2B0
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:380 → 507
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    6. NM_001321570.2 → NP_001308499.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 10

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93608.1
      UniProtKB/TrEMBL
      A0A8V8TND4, A0A8V8TPJ8
      Related
      ENSP00000514341.1, ENST00000699376.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:380 → 507
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    7. NM_001321571.2 → NP_001308500.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 11

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) encodes isoform (11, also known as delta 1).
      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS82949.1
      UniProtKB/TrEMBL
      B7Z2B0, E9PF82
      Related
      ENSP00000425824.1, ENST00000511664.6
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:380 → 507
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    8. NM_001321572.2 → NP_001308501.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 12

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13) encodes isoform (12, also known as delta 5).
      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:380 → 507
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    9. NM_001321573.2 → NP_001308502.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 13

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14) encodes isoform (13, also known as delta 11).
      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93612.1
      UniProtKB/TrEMBL
      B7Z2B0
      Related
      ENSP00000514100.1, ENST00000699048.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:371 → 498
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    10. NM_001321574.2 → NP_001308503.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 14

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15) encodes isoform (14, also known as delta 2).
      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS82950.1
      UniProtKB/TrEMBL
      B7Z2B0, D6R938
      Related
      ENSP00000514343.1, ENST00000699378.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:345 → 472
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    11. NM_001321575.2 → NP_001308504.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 15

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:360 → 487
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    12. NM_001321576.2 → NP_001308505.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 16

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17) encodes isoform (16, also known as delta 6).
      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93603.1
      UniProtKB/TrEMBL
      A0A8V8TN88, A0A8V8TND4
      Related
      ENSP00000514375.1, ENST00000699417.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:345 → 472
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    13. NM_001321577.2 → NP_001308506.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 17

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18) encodes isoform (17, also known as delta 10).
      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93601.1
      UniProtKB/TrEMBL
      A0A8V8TND4, A0A8V8TPY4
      Related
      ENSP00000514338.1, ENST00000699373.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:359 → 486
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    14. NM_001321578.2 → NP_001308507.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 18

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Conserved Domains (2) summary
      pfam08332
      Location:164 → 291
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:1 → 107
      PKc_like; Protein Kinases, catalytic domain

    15. NM_001321579.2 → NP_001308508.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 19

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4
      Related
      ENSP00000514376.1, ENST00000699418.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:380 → 507
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    16. NM_001321580.2 → NP_001308509.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 20

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21) encodes isoform (20, also known as delta 4).
      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      B7Z2B0
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:366 → 493
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    17. NM_001321581.2 → NP_001308510.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 21

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4
      Conserved Domains (2) summary
      cd14086
      Location:8 → 264
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:321 → 448
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    18. NM_001321582.2 → NP_001308511.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 22

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23) encodes isoform (22, also known as delta 7).
      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:357 → 484
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    19. NM_001321583.2 → NP_001308512.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 23

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93602.1
      UniProtKB/TrEMBL
      A0A8V8TNA7, A0A8V8TND4
      Related
      ENSP00000514345.1, ENST00000699380.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:360 → 487
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    20. NM_001321584.2 → NP_001308513.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 24

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93604.1
      UniProtKB/TrEMBL
      A0A8V8TN60, A0A8V8TND4
      Related
      ENSP00000514339.1, ENST00000699374.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:359 → 486
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    21. NM_001321585.2 → NP_001308514.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 18

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Conserved Domains (2) summary
      pfam08332
      Location:164 → 291
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:1 → 107
      PKc_like; Protein Kinases, catalytic domain

    22. NM_001321586.2 → NP_001308515.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 25

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93606.1
      UniProtKB/TrEMBL
      A0A8V8TNA1, A0A8V8TND4
      Related
      ENSP00000514340.1, ENST00000699375.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:379 → 506
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    23. NM_001321587.2 → NP_001308516.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 26

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93611.1
      UniProtKB/TrEMBL
      A0A8V8TND4, A0A994J516
      Related
      ENSP00000516209.1, ENST00000706057.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:371 → 498
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    24. NM_001321588.2 → NP_001308517.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 27

      Status: REVIEWED

      Description
      Transcript Variant: This variant (29) encodes isoform (27, also known as delta 9).
      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93605.1
      UniProtKB/TrEMBL
      A0A8V8TN65, B7Z2B0
      Related
      ENSP00000514344.1, ENST00000699379.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:359 → 486
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    25. NM_001321589.2 → NP_001308518.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS47127.1
      UniProtKB/TrEMBL
      A0A8V8TND4
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:360 → 487
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    26. NM_001321590.2 → NP_001308519.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 28

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:360 → 487
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    27. NM_001321591.2 → NP_001308520.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 29

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93610.1
      UniProtKB/TrEMBL
      A0A8V8TND4, A0A994J5B0
      Related
      ENSP00000516207.1, ENST00000706055.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:371 → 498
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    28. NM_001321592.2 → NP_001308521.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 30

      Status: REVIEWED

      Source sequence(s)
      AC004168
      UniProtKB/TrEMBL
      A0A8V8TQ10
      Conserved Domains (1) summary
      cl21453
      Location:12 → 56
      PKc_like; Protein Kinases, catalytic domain

    29. NM_001396964.1 → NP_001383893.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 31

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      B7Z2B0
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:360 → 487
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    30. NM_001396965.1 → NP_001383894.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 32

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      Consensus CDS
      CCDS93609.1
      UniProtKB/TrEMBL
      B7Z2B0
      Related
      ENSP00000423482.1, ENST00000515496.5
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:357 → 484
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    31. NM_001396966.1 → NP_001383895.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 33

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      B7Z2B0
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:356 → 483
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    32. NM_001396967.1 → NP_001383896.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 34

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:345 → 472
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    33. NM_001399855.1 → NP_001386784.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 35

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4

    34. NM_001399856.1 → NP_001386785.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 36

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4

    35. NM_001399857.1 → NP_001386786.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 37

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4

    36. NM_001399858.1 → NP_001386787.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 38

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4

    37. NM_001399859.1 → NP_001386788.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 39

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      B7Z2B0

    38. NM_001399860.1 → NP_001386789.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 40

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4

    39. NM_001399861.1 → NP_001386790.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 41

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4

    40. NM_001399862.1 → NP_001386791.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 42

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900
      UniProtKB/TrEMBL
      A0A8V8TND4

    41. NM_001399863.1 → NP_001386792.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 43

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900

    42. NM_001399864.1 → NP_001386793.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 44

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900

    43. NM_001399865.1 → NP_001386794.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 45

      Status: REVIEWED

      Source sequence(s)
      AC004056, AC004168, AC093900

    44. NM_172114.2 → NP_742112.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 5

      See identical proteins and their annotated locations for NP_742112.1

      Status: REVIEWED

      Source sequence(s)
      AB209288, AI057019, BC032784, DA113081
      Consensus CDS
      CCDS47127.1
      UniProtKB/TrEMBL
      A0A8V8TND4
      Related
      ENSP00000378030.3, ENST00000394522.7
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:360 → 487
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    45. NM_172115.3 → NP_742113.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 1

      See identical proteins and their annotated locations for NP_742113.1

      Status: REVIEWED

      Source sequence(s)
      AB209288, AI057019, AK025368, BC032784, DA113081
      Consensus CDS
      CCDS3704.1
      UniProtKB/TrEMBL
      A0A8V8TND4
      Related
      ENSP00000369098.2, ENST00000379773.6
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:346 → 473
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    46. NM_172127.3 → NP_742125.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 1

      See identical proteins and their annotated locations for NP_742125.1

      Status: REVIEWED

      Source sequence(s)
      AB209288, AC093900, AI057019, AK025368, DA113081
      Consensus CDS
      CCDS3704.1
      UniProtKB/TrEMBL
      A0A8V8TND4
      Related
      ENSP00000296402.5, ENST00000296402.9
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:346 → 473
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    47. NM_172128.3 → NP_742126.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 2

      See identical proteins and their annotated locations for NP_742126.1

      Status: REVIEWED

      Source sequence(s)
      AB209288, AC093900, AI057019, AK055642, DA113081
      Consensus CDS
      CCDS43263.1
      UniProtKB/TrEMBL
      A0A8V8TND4
      Related
      ENSP00000378032.3, ENST00000394524.7
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:346 → 473
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    48. NM_172129.2 → NP_742127.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform 4

      See identical proteins and their annotated locations for NP_742127.1

      Status: REVIEWED

      Source sequence(s)
      AB209288, AI057019, AY987011, BC032784, DA113081
      Consensus CDS
      CCDS54797.1
      UniProtKB/TrEMBL
      A0A8V8TND4
      Related
      ENSP00000422566.1, ENST00000508738.5
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:357 → 484
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      113451032..113761738 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017008674.3 → XP_016864163.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4

      UniProtKB/TrEMBL
      A0A8V8TND4
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:379 → 506
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    2. XM_047416222.1 → XP_047272178.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X3

      UniProtKB/TrEMBL
      B7Z2B0
      Related
      ENSP00000514347.1, ENST00000699382.1

    3. XM_047416221.1 → XP_047272177.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2

      UniProtKB/TrEMBL
      B7Z2B0

    4. XM_047416223.1 → XP_047272179.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X6

      UniProtKB/TrEMBL
      B7Z2B0

    5. XM_011532295.3 → XP_011530597.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X5

      See identical proteins and their annotated locations for XP_011530597.1

      UniProtKB/TrEMBL
      B7Z2B0
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:357 → 484
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    6. XM_047416220.1 → XP_047272176.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1

      UniProtKB/TrEMBL
      B7Z2B0

    7. XM_011532292.3 → XP_011530594.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X7

      See identical proteins and their annotated locations for XP_011530594.1

      Conserved Domains (2) summary
      pfam08332
      Location:251 → 378
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:1 → 174
      PKc_like; Protein Kinases, catalytic domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      116759793..117070469 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054350934.1 → XP_054206909.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4

      UniProtKB/TrEMBL
      A0A8V8TND4

    2. XM_054350933.1 → XP_054206908.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X3

      UniProtKB/TrEMBL
      B7Z2B0

    3. XM_054350932.1 → XP_054206907.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2

      UniProtKB/TrEMBL
      B7Z2B0

    4. XM_054350936.1 → XP_054206911.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X6

      UniProtKB/TrEMBL
      B7Z2B0

    5. XM_054350935.1 → XP_054206910.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X5

      UniProtKB/TrEMBL
      B7Z2B0

    6. XM_054350931.1 → XP_054206906.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1

      UniProtKB/TrEMBL
      B7Z2B0

    7. XM_054350937.1 → XP_054206912.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X8

      UniProtKB/TrEMBL
      B7Z2B0

    8. XM_054350939.1 → XP_054206914.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X7

    9. XM_054350938.1 → XP_054206913.1  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X9

      UniProtKB/TrEMBL
      A0A8V8TND4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q13557.3 GenPept UniProtKB/Swiss-Prot:Q13557

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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