RABA1c RAB GTPase homolog A1C [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: RABA1c
Official Full Name: RAB GTPase homolog A1C
Primary source: TAIR:AT5G45750
Locus tag: AT5G45750
See related: Araport:AT5G45750
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtRABA1c; MRA19.18; MRA19_18; RAB GTPase homolog A1C
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Genomic context

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See RABA1c in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 2

Sequence:: Chromosome: 5; NC_003076.8 (18559060..18560945)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Involved in determining the composition of the cell wall, particularly with respect to pectin content, possibly through regulating trafficking of pectin from the Golgi to the apoplast. [RABA1C]
Title: Null mutants of individual RABA genes impact the proportion of different cell wall components in stem tissue of Arabidopsis thaliana.
Expression of constitutively active RAB-A1c partially rescues attrs130.
Title: A specific role for Arabidopsis TRAPPII in post-Golgi trafficking that is crucial for cytokinesis and cell polarity.
The Rab-A1-mediated trafficking pathways around the trans-Golgi network, but not Rab-A1s directly, are the target of endosidin 1.
Title: Rab-A1c GTPase defines a population of the trans-Golgi network that is sensitive to endosidin1 during cytokinesis in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_123942.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell wall biogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	HDA more info	PubMed
located_in plasma membrane	HDA more info	PubMed
located_in plastid	HDA more info	PubMed
located_in vacuole	HDA more info	PubMed

General protein information

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Preferred Names: RAB GTPase homolog A1C

NP_199387.1

RAB GTPase homolog A1C (RABA1c); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane, nucleus, vacuole; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579), Rab11-related (InterPro:IPR015595); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog A1D (TAIR:AT4G18800.1); Has 28355 Blast hits to 28298 proteins in 771 species: Archae - 32; Bacteria - 162; Metazoa - 14720; Fungi - 4238; Plants - 3283; Viruses - 20; Other Eukaryotes - 5900 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

18559060..18560945

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_123942.2 → NP_199387.1 RAB GTPase homolog A1C [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_199387.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8LGG9, Q9FK68

UniProtKB/TrEMBL

A0A178UDB2, A0A5S9YCG6

Conserved Domains (1) summary

cd01868
Location:11 → 175

Rab11_like; Rab GTPase family 11 (Rab11)-like includes Rab11a, Rab11b, and Rab25