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    ATM ATM serine/threonine kinase [ Ornithorhynchus anatinus (platypus) ]

    Gene ID: 100078971, updated on 30-Apr-2024

    Summary

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    Gene symbol
    ATM
    Gene description
    ATM serine/threonine kinase
    See related
    Ensembl:ENSOANG00000006244
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ornithorhynchus anatinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
    Orthologs
    human mouse all
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    Genomic context

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    See ATM in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    64
    Annotation release Status Assembly Chr Location
    105 current mOrnAna1.pri.v4 (GCF_004115215.2) 20 NC_041747.1 (18906267..18987840, complement)

    Chromosome 20 - NC_041747.1Genomic Context describing neighboring genes Neighboring gene chromosome 20 C11orf65 homolog Neighboring gene uncharacterized LOC114805812 Neighboring gene uncharacterized LOC114805807 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene protein NPAT Neighboring gene acetyl-CoA acetyltransferase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_041747.1 Chromosome 20 Reference mOrnAna1.pri.v4 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine-protein kinase ATM
    Names
    ataxia telangiectasia mutated

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mOrnAna1.pri.v4 Primary Assembly

    Genomic

    1. NC_041747.1 Reference mOrnAna1.pri.v4 Primary Assembly

      Range
      18906267..18987840 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029047766.2 → XP_028903599.1  serine-protein kinase ATM isoform X2

      UniProtKB/TrEMBL
      A0A6I8NJZ4
      Related
      ENSOANP00000041524.1
      Conserved Domains (5) summary
      COG5032
      Location:2499 → 3062
      TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
      cd05171
      Location:2690 → 2969
      PIKKc_ATM; Catalytic domain of Ataxia Telangiectasia Mutated
      pfam02259
      Location:2104 → 2496
      FAT; FAT domain
      pfam11640
      Location:8 → 164
      TAN; Telomere-length maintenance and DNA damage repair
      cl19765
      Location:1154 → 1250
      mTERF

    2. XM_029047765.2 → XP_028903598.1  serine-protein kinase ATM isoform X1

      UniProtKB/TrEMBL
      A0A6I8NJZ4
      Conserved Domains (5) summary
      COG5032
      Location:2500 → 3063
      TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
      cd05171
      Location:2691 → 2970
      PIKKc_ATM; Catalytic domain of Ataxia Telangiectasia Mutated
      pfam02259
      Location:2105 → 2497
      FAT; FAT domain
      pfam11640
      Location:8 → 164
      TAN; Telomere-length maintenance and DNA damage repair
      cl19765
      Location:1154 → 1250
      mTERF

    3. XM_029047767.1 → XP_028903600.1  serine-protein kinase ATM isoform X3

      UniProtKB/TrEMBL
      A0A6I8N858
      Conserved Domains (5) summary
      COG5032
      Location:2407 → 2970
      TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
      cd05171
      Location:2598 → 2877
      PIKKc_ATM; Catalytic domain of Ataxia Telangiectasia Mutated
      pfam02259
      Location:2012 → 2404
      FAT; FAT domain
      pfam11640
      Location:1 → 71
      TAN; Telomere-length maintenance and DNA damage repair
      cl19765
      Location:1061 → 1157
      mTERF

    RNA

    1. XR_003753828.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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