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    UNC5A unc-5 netrin receptor A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705285, updated on 17-Aug-2024

    Summary

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    Official Symbol
    UNC5Aprovided by VGNC
    Official Full Name
    unc-5 netrin receptor Aprovided by VGNC
    Primary source
    VGNC:VGNC:78721
    See related
    Ensembl:ENSMMUG00000002649
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See UNC5A in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (174269394..174341191)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (175322882..175392742)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene tetraspanin 17 Neighboring gene uncharacterized LOC106999048 Neighboring gene uncharacterized LOC114678982 Neighboring gene heat shock factor-binding protein 1 pseudogene Neighboring gene hexokinase 3 Neighboring gene ubiquitin interaction motif containing 1 Neighboring gene zinc finger protein 346

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables netrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anterior/posterior axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in netrin-activated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    netrin receptor UNC5A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      174269394..174341191
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028849932.1 → XP_028705765.1  netrin receptor UNC5A isoform X4

      UniProtKB/TrEMBL
      F7H4X4, H9F8Y6
      Related
      ENSMMUP00000003571.3, ENSMMUT00000003779.3
      Conserved Domains (6) summary
      smart00218
      Location:495 → 598
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      smart00209
      Location:245 → 296
      TSP1; Thrombospondin type 1 repeats
      cd08800
      Location:811 → 894
      Death_UNC5A; Death domain found in Uncoordinated-5A
      pfam17217
      Location:645 → 784
      UPA; UPA domain
      cd00096
      Location:157 → 161
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:153 → 239
      Ig; Immunoglobulin domain

    2. XM_028849933.1 → XP_028705766.1  netrin receptor UNC5A isoform X5

      UniProtKB/TrEMBL
      F7H510, H9F8Y6
      Related
      ENSMMUP00000003568.4, ENSMMUT00000003776.4
      Conserved Domains (6) summary
      smart00218
      Location:439 → 542
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      smart00209
      Location:245 → 293
      TSP1; Thrombospondin type 1 repeats
      cd08800
      Location:755 → 838
      Death_UNC5A; Death domain found in Uncoordinated-5A
      pfam17217
      Location:589 → 728
      UPA; UPA domain
      cd00096
      Location:157 → 161
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:153 → 239
      Ig; Immunoglobulin domain

    3. XM_028849929.1 → XP_028705762.1  netrin receptor UNC5A isoform X1

      UniProtKB/TrEMBL
      H9F8Y6
      Conserved Domains (5) summary
      smart00218
      Location:580 → 683
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      smart00209
      Location:315 → 366
      TSP1; Thrombospondin type 1 repeats
      cd08800
      Location:896 → 979
      Death_UNC5A; Death domain found in Uncoordinated-5A
      pfam17217
      Location:730 → 869
      UPA; UPA domain
      cl11960
      Location:223 → 309
      Ig; Immunoglobulin domain

    4. XM_028849930.1 → XP_028705763.1  netrin receptor UNC5A isoform X2

      UniProtKB/TrEMBL
      H9F8Y6
      Conserved Domains (5) summary
      smart00218
      Location:565 → 668
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      smart00209
      Location:315 → 366
      TSP1; Thrombospondin type 1 repeats
      cd08800
      Location:881 → 964
      Death_UNC5A; Death domain found in Uncoordinated-5A
      pfam17217
      Location:715 → 854
      UPA; UPA domain
      cl11960
      Location:223 → 309
      Ig; Immunoglobulin domain

    5. XM_028849931.1 → XP_028705764.1  netrin receptor UNC5A isoform X3

      UniProtKB/TrEMBL
      H9F8Y6
      Conserved Domains (5) summary
      smart00218
      Location:509 → 612
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      smart00209
      Location:315 → 363
      TSP1; Thrombospondin type 1 repeats
      cd08800
      Location:825 → 908
      Death_UNC5A; Death domain found in Uncoordinated-5A
      pfam17217
      Location:659 → 798
      UPA; UPA domain
      cl11960
      Location:223 → 309
      Ig; Immunoglobulin domain
    Nucleotide Protein
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