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    NCR3 natural cytotoxicity triggering receptor 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715574, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NCR3provided by VGNC
    Official Full Name
    natural cytotoxicity triggering receptor 3provided by VGNC
    Primary source
    VGNC:VGNC:74990
    See related
    Ensembl:ENSMMUG00000008854
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    NKp30
    Orthologs
    human all
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    Genomic context

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    See NCR3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (137919086..137923382)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (32448815..32452995, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene proline rich coiled-coil 2A Neighboring gene small nucleolar RNA SNORA38 Neighboring gene allograft inflammatory factor 1 Neighboring gene leukocyte specific transcript 1 Neighboring gene lymphotoxin beta Neighboring gene tumor necrosis factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular and functional characterization of NKG2D, NKp80, and NKG2C triggering NK cell receptors in rhesus and cynomolgus macaques: monitoring of NK cell function during simian HIV infection. Biassoni R, et al. J Immunol, 2005 May 1. PMID 15843571
    2. Rhesus macaque class I duplicon structures, organization, and evolution within the alpha block of the major histocompatibility complex. Kulski JK, et al. Mol Biol Evol, 2004 Nov. PMID 15269276
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in immune response-activating cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in natural killer cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of natural killer cell mediated cytotoxicity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    natural cytotoxicity triggering receptor 3
    Names
    NK-p30
    natural killer cell p30-related protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042640.1 → NP_001036105.1  natural cytotoxicity triggering receptor 3 precursor

      See identical proteins and their annotated locations for NP_001036105.1

      Status: PROVISIONAL

      Source sequence(s)
      AY035214
      UniProtKB/Swiss-Prot
      Q8MJ02
      Conserved Domains (2) summary
      smart00410
      Location:24 → 127
      IG_like; Immunoglobulin like
      pfam07686
      Location:23 → 127
      V-set; Immunoglobulin V-set domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      137919086..137923382
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015135930.2 → XP_014991416.2  natural cytotoxicity triggering receptor 3 isoform X2

      Conserved Domains (1) summary
      pfam07686
      Location:23 → 127
      V-set; Immunoglobulin V-set domain

    2. XM_015135931.2 → XP_014991417.2  natural cytotoxicity triggering receptor 3 isoform X4

      Conserved Domains (1) summary
      cd20926
      Location:18 → 129
      IgV_NKp30; Immunoglobulin variable (IgV) domain of Natural Killer cell activating receptor NKp30 and similar domains

    3. XM_028846837.1 → XP_028702670.1  natural cytotoxicity triggering receptor 3 isoform X5

      UniProtKB/Swiss-Prot
      Q5TM24, Q8MJ00, Q8MJ01, Q8MJ02
      UniProtKB/TrEMBL
      A0A140TAV2, G7MRI6
      Related
      ENSMMUP00000011616.3, ENSMMUT00000012386.3
      Conserved Domains (1) summary
      pfam07686
      Location:23 → 127
      V-set; Immunoglobulin V-set domain

    4. XM_028846835.1 → XP_028702668.1  natural cytotoxicity triggering receptor 3 isoform X1

      Conserved Domains (1) summary
      pfam07686
      Location:45 → 149
      V-set; Immunoglobulin V-set domain

    5. XM_028846836.1 → XP_028702669.1  natural cytotoxicity triggering receptor 3 isoform X3

      UniProtKB/TrEMBL
      A0A140TAV2
      Conserved Domains (1) summary
      cd20926
      Location:40 → 151
      IgV_NKp30; Immunoglobulin variable (IgV) domain of Natural Killer cell activating receptor NKp30 and similar domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MJ02.2 GenPept UniProtKB/Swiss-Prot:Q8MJ02

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