DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: DYRK1Aprovided by VGNC
Official Full Name: dual specificity tyrosine phosphorylation regulated kinase 1Aprovided by VGNC
Primary source: VGNC:VGNC:72015
See related: Ensembl:ENSMMUG00000018131
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	3	NC_041756.1 (9123630..9273268, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	3	NC_027895.1 (9243908..9339839, complement)

Chromosome 3 - NC_041756.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

SHGC-51948 (e-PCR)
- UniSTS:26628

STS-G06294 (e-PCR)
- UniSTS:10505

DYRK1A__4795 (e-PCR)
- UniSTS:462887

DYRK1A (e-PCR)
- UniSTS:278323

SHGC-63617 (e-PCR)
- UniSTS:43866

DYRK1A (e-PCR)
- UniSTS:506204

D21S1972 (e-PCR)
- UniSTS:378

D11Wox11 (e-PCR)
- UniSTS:518811

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine/tyrosine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables transcription coactivator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in peptidyl-serine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-threonine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein autophosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dual specificity tyrosine-phosphorylation-regulated kinase 1A

Names: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

NP_001245072.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_014988369.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_028700611.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_028700612.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_028700613.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_028700614.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_028700615.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_028700616.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001258143.2 → NP_001245072.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A

See identical proteins and their annotated locations for NP_001245072.1

Status: PROVISIONAL

Source sequence(s)

JU474572

UniProtKB/TrEMBL

F7FBT7, I0FH67

Related

ENSMMUP00000023835.3, ENSMMUT00000025477.4

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041756.1 Reference Mmul_10 Primary Assembly

Range

9123630..9273268 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028844781.1 → XP_028700614.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2

UniProtKB/TrEMBL

F7FBT2, F7FBT7

Related

ENSMMUP00000023836.4, ENSMMUT00000025478.4

Conserved Domains (1) summary

cd14226
Location:139 → 475

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_028844778.1 → XP_028700611.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

UniProtKB/TrEMBL

F7FBT7, I0FH67

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_015132883.2 → XP_014988369.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3

UniProtKB/TrEMBL

G7MMS8

Conserved Domains (1) summary

cd14226
Location:119 → 455

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_028844779.1 → XP_028700612.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

UniProtKB/TrEMBL

F7FBT7, I0FH67

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_028844782.1 → XP_028700615.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2

UniProtKB/TrEMBL

F7FBT2, F7FBT7

Conserved Domains (1) summary

cd14226
Location:139 → 475

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_028844780.1 → XP_028700613.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

UniProtKB/TrEMBL

F7FBT7, I0FH67

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_028844783.1 → XP_028700616.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X4

UniProtKB/TrEMBL

G7MMS8

Conserved Domains (1) summary

cd14226
Location:110 → 446

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1