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    AXIN2 axin 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718566, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AXIN2provided by VGNC
    Official Full Name
    axin 2provided by VGNC
    Primary source
    VGNC:VGNC:104582
    See related
    Ensembl:ENSMMUG00000060015
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    axin-2
    Orthologs
    human mouse all
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    Genomic context

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    See AXIN2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (61924121..61957598, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (59004180..59036808, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106994101 Neighboring gene uncharacterized LOC114673174 Neighboring gene regulator of G protein signaling 9 Neighboring gene uncharacterized LOC114673175 Neighboring gene chloride intracellular channel protein 1-like Neighboring gene centrosomal protein 112 Neighboring gene nuclear transport factor 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in negative regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    axin-2
    Names
    axin-2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      61924121..61957598 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028836679.1 → XP_028692512.1  axin-2 isoform X4

      UniProtKB/TrEMBL
      A0A5F7ZJQ2, H9ZE47
      Related
      ENSMMUP00000065857.1, ENSMMUT00000092031.1
      Conserved Domains (4) summary
      cd08707
      Location:82 → 198
      RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
      smart00021
      Location:715 → 797
      DAX; Domain present in Dishevelled and axin
      cd11582
      Location:12 → 73
      Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
      pfam08833
      Location:451 → 486
      Axin_b-cat_bind; Axin beta-catenin binding domain

    2. XM_028836678.1 → XP_028692511.1  axin-2 isoform X3

      UniProtKB/TrEMBL
      A0A5F8ADI7, H9ZE47
      Related
      ENSMMUP00000075936.1, ENSMMUT00000092660.1
      Conserved Domains (4) summary
      cd08707
      Location:82 → 198
      RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
      smart00021
      Location:748 → 830
      DAX; Domain present in Dishevelled and axin
      cd11582
      Location:12 → 73
      Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
      pfam08833
      Location:451 → 486
      Axin_b-cat_bind; Axin beta-catenin binding domain

    3. XM_028836676.1 → XP_028692509.1  axin-2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AE66, H9ZE47
      Related
      ENSMMUP00000070922.1, ENSMMUT00000099906.1
      Conserved Domains (4) summary
      cd08707
      Location:82 → 198
      RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
      smart00021
      Location:780 → 862
      DAX; Domain present in Dishevelled and axin
      cd11582
      Location:12 → 73
      Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
      pfam08833
      Location:451 → 486
      Axin_b-cat_bind; Axin beta-catenin binding domain

    4. XM_015120135.2 → XP_014975621.2  axin-2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AE66, H9ZE47
      Related
      ENSMMUP00000076172.1, ENSMMUT00000080252.1
      Conserved Domains (4) summary
      cd08707
      Location:82 → 198
      RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
      smart00021
      Location:780 → 862
      DAX; Domain present in Dishevelled and axin
      cd11582
      Location:12 → 73
      Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
      pfam08833
      Location:451 → 486
      Axin_b-cat_bind; Axin beta-catenin binding domain

    5. XM_028836677.1 → XP_028692510.1  axin-2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AE66, H9ZE47
      Conserved Domains (4) summary
      cd08707
      Location:82 → 198
      RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
      smart00021
      Location:780 → 862
      DAX; Domain present in Dishevelled and axin
      cd11582
      Location:12 → 73
      Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
      pfam08833
      Location:451 → 486
      Axin_b-cat_bind; Axin beta-catenin binding domain

    6. XM_015120136.2 → XP_014975622.2  axin-2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AE66, H9ZE47
      Conserved Domains (4) summary
      cd08707
      Location:82 → 198
      RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
      smart00021
      Location:780 → 862
      DAX; Domain present in Dishevelled and axin
      cd11582
      Location:12 → 73
      Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
      pfam08833
      Location:451 → 486
      Axin_b-cat_bind; Axin beta-catenin binding domain

    7. XM_015120139.2 → XP_014975625.2  axin-2 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZD68, H9ZE47
      Related
      ENSMMUP00000062552.1, ENSMMUT00000091776.1
      Conserved Domains (4) summary
      cd08707
      Location:82 → 198
      RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
      smart00021
      Location:762 → 844
      DAX; Domain present in Dishevelled and axin
      cd11582
      Location:12 → 73
      Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
      pfam08833
      Location:433 → 468
      Axin_b-cat_bind; Axin beta-catenin binding domain

    8. XM_028836680.1 → XP_028692513.1  axin-2 isoform X5

      UniProtKB/TrEMBL
      H9ZE47
      Conserved Domains (4) summary
      cd08707
      Location:82 → 198
      RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
      smart00021
      Location:697 → 779
      DAX; Domain present in Dishevelled and axin
      cd11582
      Location:12 → 73
      Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
      pfam08833
      Location:433 → 468
      Axin_b-cat_bind; Axin beta-catenin binding domain
    Nucleotide Protein
    Heading Accession and Version

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