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    ADAP2 ArfGAP with dual PH domains 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713749, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAP2provided by VGNC
    Official Full Name
    ArfGAP with dual PH domains 2provided by VGNC
    Primary source
    VGNC:VGNC:69430
    See related
    Ensembl:ENSMMUG00000009077
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    CENTA2
    Orthologs
    human mouse all
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    Genomic context

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    See ADAP2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (28454547..28493533)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (24876483..24918955)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114673090 Neighboring gene transcription elongation factor, mitochondrial Neighboring gene 40S ribosomal protein S27-like Neighboring gene divergent paired-related homeobox-like Neighboring gene uncharacterized LOC114673091 Neighboring gene ring finger protein 135 Neighboring gene ras homolog family member T1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with dual PH domain-containing protein 2
    Names
    centaurin, alpha 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      28454547..28493533
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001112623.4 → XP_001112623.2  arf-GAP with dual PH domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A5F8APV4, H9F5I0
      Related
      ENSMMUP00000079413.1, ENSMMUT00000102776.1
      Conserved Domains (3) summary
      cd01251
      Location:255 → 362
      PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
      cd13252
      Location:133 → 241
      PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
      cd08844
      Location:4 → 117
      ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains

    2. XM_028836189.1 → XP_028692022.1  arf-GAP with dual PH domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A5F7ZMY3, H9F5I0
      Related
      ENSMMUP00000066536.1, ENSMMUT00000101739.1
      Conserved Domains (3) summary
      cd13252
      Location:133 → 241
      PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
      cd08844
      Location:4 → 117
      ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains
      cl17171
      Location:255 → 336
      PH-like; Pleckstrin homology-like domain

    3. XM_015118993.2 → XP_014974479.2  arf-GAP with dual PH domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      H9F5I0
      Conserved Domains (3) summary
      cd01251
      Location:255 → 362
      PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
      cd13252
      Location:133 → 241
      PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
      cd08844
      Location:4 → 117
      ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains

    4. XM_028836188.1 → XP_028692021.1  arf-GAP with dual PH domain-containing protein 2 isoform X4

      UniProtKB/TrEMBL
      H9F5I0
      Conserved Domains (3) summary
      cd13252
      Location:133 → 241
      PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
      cd08844
      Location:4 → 117
      ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains
      cl17171
      Location:255 → 336
      PH-like; Pleckstrin homology-like domain

    5. XM_028836187.1 → XP_028692020.1  arf-GAP with dual PH domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      H9F5I0
      Conserved Domains (3) summary
      cd13252
      Location:133 → 241
      PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
      cd08844
      Location:4 → 117
      ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains
      cl17171
      Location:248 → 341
      PH-like; Pleckstrin homology-like domain

    6. XM_015118994.2 → XP_014974480.2  arf-GAP with dual PH domain-containing protein 2 isoform X5

      UniProtKB/TrEMBL
      H9F5I0
      Related
      ENSMMUP00000011908.4, ENSMMUT00000012698.4
      Conserved Domains (3) summary
      cd01251
      Location:227 → 334
      PH2_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 2
      cd13252
      Location:133 → 219
      PH1_ADAP; ArfGAP with dual PH domains Pleckstrin homology (PH) domain, repeat 1
      cd08844
      Location:4 → 117
      ArfGap_ADAP2; ADAP2 GTPase activating protein for Arf, with dual PH domains
    Nucleotide Protein
    Heading Accession and Version

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