DAPK1 death associated protein kinase 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: DAPK1provided by VGNC
Official Full Name: death associated protein kinase 1provided by VGNC
Primary source: VGNC:VGNC:71732
Locus tag: EGK_07830
See related: Ensembl:ENSMMUG00000017053
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 15

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	15	NC_041768.1 (102623713..102833012)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	15	NC_027907.1 (103698145..103908854)

Chromosome 15 - NC_041768.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

SHGC-148843 (e-PCR)
- UniSTS:176641

D9S2045 (e-PCR)
- UniSTS:13338

SHGC-33610 (e-PCR)
- UniSTS:5933

RH18220 (e-PCR)
- UniSTS:21550

STS-X76104 (e-PCR)
- UniSTS:51017

STS-N34470 (e-PCR)
- UniSTS:79970

SHGC-2351 (e-PCR)
- UniSTS:46760

WI-17027 (e-PCR)
- UniSTS:27104

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables TIR domain binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in MyD88-dependent toll-like receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: death-associated protein kinase 1

NP_001244717.1

EC 2.7.1.-

EC 2.7.11.1

XP_014973500.1

EC 2.7.1.-

EC 2.7.11.1

XP_014973501.1

EC 2.7.1.-

EC 2.7.11.1

XP_028690046.1

EC 2.7.1.-

EC 2.7.11.1

XP_028690047.1

EC 2.7.1.-

EC 2.7.11.1

XP_028690048.1

EC 2.7.1.-

EC 2.7.11.1

XP_028690049.1

EC 2.7.1.-

EC 2.7.11.1

XP_028690050.1

EC 2.7.1.-

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001257788.1 → NP_001244717.1 death-associated protein kinase 1

See identical proteins and their annotated locations for NP_001244717.1

Status: PROVISIONAL

Source sequence(s)

JU321974

UniProtKB/TrEMBL

A0A5F7ZJJ0, A0A8J8XUA8, F7HLL1, G7NGF7

Related

ENSMMUP00000065775.1, ENSMMUT00000080452.1

Conserved Domains (7) summary

smart00220
Location:13 → 275

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd00204
Location:505 → 629

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd08782
Location:1308 → 1393

Death_DAPK1; Death domain found in death-associated protein kinase 1

cd14194
Location:7 → 275

STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1

pfam12796
Location:416 → 508

Ank_2; Ankyrin repeats (3 copies)

pfam13637
Location:513 → 564

Ank_4; Ankyrin repeats (many copies)

sd00045
Location:412 → 442

ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041768.1 Reference Mmul_10 Primary Assembly

Range

102623713..102833012

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015118014.2 → XP_014973500.1 death-associated protein kinase 1 isoform X2

UniProtKB/TrEMBL

A0A5F7ZJJ0, A0A8J8XUA8, F7HLL1, G7NGF7

Conserved Domains (7) summary

smart00220
Location:13 → 275

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd00204
Location:505 → 629

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd08782
Location:1308 → 1393

Death_DAPK1; Death domain found in death-associated protein kinase 1

cd14194
Location:7 → 275

STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1

pfam12796
Location:416 → 508

Ank_2; Ankyrin repeats (3 copies)

pfam13637
Location:513 → 564

Ank_4; Ankyrin repeats (many copies)

sd00045
Location:412 → 442

ANK; ANK repeat [structural motif]
XM_028834213.1 → XP_028690046.1 death-associated protein kinase 1 isoform X1

UniProtKB/TrEMBL

F7HLL1, F7HNL1

Conserved Domains (5) summary

PLN03192
Location:515 → 768

PLN03192; Voltage-dependent potassium channel; Provisional

PHA03100
Location:367 → 639

PHA03100; ankyrin repeat protein; Provisional

cd08782
Location:1308 → 1393

Death_DAPK1; Death domain found in death-associated protein kinase 1

cd14194
Location:7 → 275

STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1

sd00045
Location:412 → 442

ANK; ANK repeat [structural motif]
XM_028834215.1 → XP_028690048.1 death-associated protein kinase 1 isoform X1

UniProtKB/TrEMBL

F7HLL1, F7HNL1

Conserved Domains (5) summary

PLN03192
Location:515 → 768

PLN03192; Voltage-dependent potassium channel; Provisional

PHA03100
Location:367 → 639

PHA03100; ankyrin repeat protein; Provisional

cd08782
Location:1308 → 1393

Death_DAPK1; Death domain found in death-associated protein kinase 1

cd14194
Location:7 → 275

STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1

sd00045
Location:412 → 442

ANK; ANK repeat [structural motif]
XM_028834216.1 → XP_028690049.1 death-associated protein kinase 1 isoform X1

UniProtKB/TrEMBL

F7HLL1, F7HNL1

Conserved Domains (5) summary

PLN03192
Location:515 → 768

PLN03192; Voltage-dependent potassium channel; Provisional

PHA03100
Location:367 → 639

PHA03100; ankyrin repeat protein; Provisional

cd08782
Location:1308 → 1393

Death_DAPK1; Death domain found in death-associated protein kinase 1

cd14194
Location:7 → 275

STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1

sd00045
Location:412 → 442

ANK; ANK repeat [structural motif]
XM_015118015.2 → XP_014973501.1 death-associated protein kinase 1 isoform X2

UniProtKB/TrEMBL

A0A5F7ZJJ0, A0A8J8XUA8, F7HLL1, G7NGF7

Conserved Domains (7) summary

smart00220
Location:13 → 275

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd00204
Location:505 → 629

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd08782
Location:1308 → 1393

Death_DAPK1; Death domain found in death-associated protein kinase 1

cd14194
Location:7 → 275

STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1

pfam12796
Location:416 → 508

Ank_2; Ankyrin repeats (3 copies)

pfam13637
Location:513 → 564

Ank_4; Ankyrin repeats (many copies)

sd00045
Location:412 → 442

ANK; ANK repeat [structural motif]
XM_028834214.1 → XP_028690047.1 death-associated protein kinase 1 isoform X1

UniProtKB/TrEMBL

F7HLL1, F7HNL1

Related

ENSMMUP00000022443.4, ENSMMUT00000023978.4

Conserved Domains (5) summary

PLN03192
Location:515 → 768

PLN03192; Voltage-dependent potassium channel; Provisional

PHA03100
Location:367 → 639

PHA03100; ankyrin repeat protein; Provisional

cd08782
Location:1308 → 1393

Death_DAPK1; Death domain found in death-associated protein kinase 1

cd14194
Location:7 → 275

STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1

sd00045
Location:412 → 442

ANK; ANK repeat [structural motif]
XM_028834217.1 → XP_028690050.1 death-associated protein kinase 1 isoform X3

UniProtKB/TrEMBL

F7HLL1

Conserved Domains (7) summary

PLN03192
Location:370 → 623

PLN03192; Voltage-dependent potassium channel; Provisional

PHA03100
Location:222 → 494

PHA03100; ankyrin repeat protein; Provisional

cd08782
Location:1163 → 1248

Death_DAPK1; Death domain found in death-associated protein kinase 1

sd00045
Location:267 → 297

ANK; ANK repeat [structural motif]

pfam16095
Location:860 → 1028

COR; C-terminal of Roc, COR, domain

cl21453
Location:1 → 130

PKc_like; Protein Kinases, catalytic domain

cl21455
Location:644 → 745

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases