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    PDE1A phosphodiesterase 1A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705555, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PDE1Aprovided by VGNC
    Official Full Name
    phosphodiesterase 1Aprovided by VGNC
    Primary source
    VGNC:VGNC:75909
    See related
    Ensembl:ENSMMUG00000001163
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PDE1A in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (69239204..69700955, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (69210838..69355105, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene keratin, type I cytoskeletal 18 pseudogene Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 1C Neighboring gene actin-1-like Neighboring gene uncharacterized LOC114671523 Neighboring gene DnaJ heat shock protein family (Hsp40) member C10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3',5'-cyclic-nucleotide phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
    Names
    phosphodiesterase 1A, calmodulin-dependent
    NP_001244513.1
    XP_028686356.1
    XP_028686357.1
    XP_028686358.1
    XP_028686359.1
    XP_028686360.1
    XP_028686361.1
    XP_028686362.1
    XP_028686363.1
    XP_028686364.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257584.1 → NP_001244513.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

      See identical proteins and their annotated locations for NP_001244513.1

      Status: PROVISIONAL

      Source sequence(s)
      JU334868
      UniProtKB/TrEMBL
      F6RHA7, H9FVG2
      Related
      ENSMMUP00000042368.1, ENSMMUT00000056229.2
      Conserved Domains (2) summary
      pfam08499
      Location:77 → 133
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      pfam00233
      Location:218 → 434
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      69239204..69700955 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028830525.1 → XP_028686358.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X3

      UniProtKB/TrEMBL
      F6RHA7, H9FVG2
      Conserved Domains (2) summary
      pfam08499
      Location:77 → 133
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      pfam00233
      Location:218 → 434
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    2. XM_028830530.1 → XP_028686363.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X7

      UniProtKB/TrEMBL
      F6RH80
      Conserved Domains (2) summary
      pfam08499
      Location:43 → 99
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      pfam00233
      Location:184 → 400
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    3. XM_028830528.1 → XP_028686361.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X5

      UniProtKB/TrEMBL
      A0A1D5Q5X8, A0A5F8ACX5
      Related
      ENSMMUP00000075788.1, ENSMMUT00000094549.1
      Conserved Domains (2) summary
      pfam08499
      Location:61 → 117
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      pfam00233
      Location:202 → 418
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    4. XM_028830526.1 → XP_028686359.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X4

      UniProtKB/TrEMBL
      A0A1D5Q5X8
      Conserved Domains (2) summary
      pfam08499
      Location:77 → 133
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      pfam00233
      Location:218 → 434
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    5. XM_028830527.1 → XP_028686360.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X4

      UniProtKB/TrEMBL
      A0A1D5Q5X8
      Conserved Domains (2) summary
      pfam08499
      Location:77 → 133
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      pfam00233
      Location:218 → 434
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    6. XM_028830523.1 → XP_028686356.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZPM7
      Related
      ENSMMUP00000067572.1, ENSMMUT00000079905.1
      Conserved Domains (2) summary
      pfam08499
      Location:77 → 133
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      pfam00233
      Location:218 → 434
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    7. XM_028830529.1 → XP_028686362.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X6

      UniProtKB/TrEMBL
      A0A1D5Q5X8, F6RHC6
      Related
      ENSMMUP00000001552.4, ENSMMUT00000001648.4
      Conserved Domains (2) summary
      pfam08499
      Location:61 → 117
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      pfam00233
      Location:202 → 418
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    8. XM_028830531.1 → XP_028686364.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X8

      UniProtKB/TrEMBL
      F6RH80
      Related
      ENSMMUP00000001558.4, ENSMMUT00000001654.4
      Conserved Domains (2) summary
      pfam08499
      Location:43 → 99
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      pfam00233
      Location:184 → 400
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    9. XM_028830524.1 → XP_028686357.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q5X8
      Conserved Domains (2) summary
      pfam08499
      Location:77 → 133
      PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal
      pfam00233
      Location:218 → 434
      PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

    RNA

    1. XR_003721163.1 RNA Sequence

    2. XR_003721166.1 RNA Sequence

    3. XR_003721164.1 RNA Sequence

    4. XR_003721167.1 RNA Sequence

    5. XR_003721165.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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