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    TPX2 TPX2 microtubule nucleation factor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712961, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TPX2provided by VGNC
    Official Full Name
    TPX2 microtubule nucleation factorprovided by VGNC
    Primary source
    VGNC:VGNC:78697
    See related
    Ensembl:ENSMMUG00000000966
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TPX2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (66982697..67045885)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (32279873..32342083, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit 4I2 Neighboring gene BCL2 like 1 Neighboring gene uncharacterized LOC114670461 Neighboring gene myosin light chain kinase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in activation of protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of mitotic spindle organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    targeting protein for Xklp2
    Names
    TPX2, microtubule-associated, homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      66982697..67045885
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015149283.2 → XP_015004769.2  targeting protein for Xklp2

      UniProtKB/TrEMBL
      A0A1D5R6L0, A0A5S6RC19, A0A8J8YIQ1, G7N550, H9Z6J9
      Conserved Domains (3) summary
      pfam09041
      Location:1 → 68
      Aurora-A_bind; Aurora-A binding
      pfam06886
      Location:661 → 717
      TPX2; Targeting protein for Xklp2 (TPX2)
      pfam12214
      Location:366 → 488
      TPX2_importin; Cell cycle regulated microtubule associated protein

    2. XM_015149280.2 → XP_015004766.2  targeting protein for Xklp2

      UniProtKB/TrEMBL
      A0A1D5R6L0, A0A5S6RC19, A0A8J8YIQ1, G7N550, H9Z6J9
      Related
      ENSMMUP00000059049.2, ENSMMUT00000074900.2
      Conserved Domains (3) summary
      pfam09041
      Location:1 → 68
      Aurora-A_bind; Aurora-A binding
      pfam06886
      Location:661 → 717
      TPX2; Targeting protein for Xklp2 (TPX2)
      pfam12214
      Location:366 → 488
      TPX2_importin; Cell cycle regulated microtubule associated protein

    3. XM_015149281.2 → XP_015004767.2  targeting protein for Xklp2

      UniProtKB/TrEMBL
      A0A1D5R6L0, A0A5S6RC19, A0A8J8YIQ1, G7N550, H9Z6J9
      Conserved Domains (3) summary
      pfam09041
      Location:1 → 68
      Aurora-A_bind; Aurora-A binding
      pfam06886
      Location:661 → 717
      TPX2; Targeting protein for Xklp2 (TPX2)
      pfam12214
      Location:366 → 488
      TPX2_importin; Cell cycle regulated microtubule associated protein

    4. XM_015149284.2 → XP_015004770.2  targeting protein for Xklp2

      UniProtKB/TrEMBL
      A0A1D5R6L0, A0A5S6RC19, A0A8J8YIQ1, G7N550, H9Z6J9
      Conserved Domains (3) summary
      pfam09041
      Location:1 → 68
      Aurora-A_bind; Aurora-A binding
      pfam06886
      Location:661 → 717
      TPX2; Targeting protein for Xklp2 (TPX2)
      pfam12214
      Location:366 → 488
      TPX2_importin; Cell cycle regulated microtubule associated protein

    5. XM_028828290.1 → XP_028684123.1  targeting protein for Xklp2

      UniProtKB/TrEMBL
      A0A1D5R6L0, A0A5S6RC19, A0A8J8YIQ1, G7N550, H9Z6J9
      Related
      ENSMMUP00000055948.2, ENSMMUT00000058014.2
      Conserved Domains (3) summary
      pfam09041
      Location:1 → 68
      Aurora-A_bind; Aurora-A binding
      pfam06886
      Location:661 → 717
      TPX2; Targeting protein for Xklp2 (TPX2)
      pfam12214
      Location:366 → 488
      TPX2_importin; Cell cycle regulated microtubule associated protein

    6. XM_028828289.1 → XP_028684122.1  targeting protein for Xklp2

      UniProtKB/TrEMBL
      A0A1D5R6L0, A0A5S6RC19, A0A8J8YIQ1, G7N550, H9Z6J9
      Related
      ENSMMUP00000066338.1, ENSMMUT00000088548.1
      Conserved Domains (3) summary
      pfam09041
      Location:1 → 68
      Aurora-A_bind; Aurora-A binding
      pfam06886
      Location:661 → 717
      TPX2; Targeting protein for Xklp2 (TPX2)
      pfam12214
      Location:366 → 488
      TPX2_importin; Cell cycle regulated microtubule associated protein

    7. XM_028828291.1 → XP_028684124.1  targeting protein for Xklp2

      UniProtKB/TrEMBL
      A0A1D5R6L0, A0A5S6RC19, A0A8J8YIQ1, G7N550, H9Z6J9
      Related
      ENSMMUP00000067233.1, ENSMMUT00000082565.1
      Conserved Domains (3) summary
      pfam09041
      Location:1 → 68
      Aurora-A_bind; Aurora-A binding
      pfam06886
      Location:661 → 717
      TPX2; Targeting protein for Xklp2 (TPX2)
      pfam12214
      Location:366 → 488
      TPX2_importin; Cell cycle regulated microtubule associated protein
    Nucleotide Protein
    Heading Accession and Version

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