CCKLR-17D1 Cholecystokinin-like receptor at 17D1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CCKLR-17D1provided by FlyBase
Official Full Name: Cholecystokinin-like receptor at 17D1provided by FlyBase
Primary source: FLYBASE:FBgn0259231
Locus tag: Dmel_CG42301
See related: AllianceGenome:FB:FBgn0259231
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0170980.61; anon-WO0170980.62; CCK like R; CCKLR; CCKLR-17D1-R; CCKLR-D1; CCKLR17D1; CG42301; CG6857; Dm CG6857; Dmel\CG42301; DSK-R2; DskR-2; SK-R
Old locus tag: Dmel_CG6857
Summary: Enables neuropeptide receptor activity. Involved in several processes, including adult locomotory behavior; larval locomotory behavior; and neuropeptide signaling pathway. Acts upstream of with a negative effect on inter-male aggressive behavior. Located in neuronal cell body and plasma membrane. Colocalizes with terminal bouton. Human ortholog(s) of this gene implicated in obesity and pancreatic cancer. Orthologous to human CCKAR (cholecystokinin A receptor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (18707494..18726572, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (18601527..18620605, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables G protein-coupled receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
NOT enables cholecystokinin receptor activity	IDA Inferred from Direct Assay more info	PubMed
NOT enables gastrin receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables neuropeptide receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables neuropeptide receptor activity	IPI Inferred from Physical Interaction more info	PubMed
enables neuropeptide receptor activity	ISM Inferred from Sequence Model more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in G protein-coupled receptor signaling pathway	ISM Inferred from Sequence Model more info	PubMed
involved_in G protein-coupled receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in adult locomotory behavior	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_negative_effect inter-male aggressive behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in larval locomotory behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in multicellular organismal response to stress	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuromuscular junction development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuropeptide signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuropeptide signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of cytosolic calcium ion concentration	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISM Inferred from Sequence Model more info	PubMed
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in neuronal cell body	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
colocalizes_with terminal bouton	IDA Inferred from Direct Assay more info	PubMed

Names: CCK-like receptor at 17D1; CCKLR-17D1-PA; CG42301-PA; cholecystokinin-like receptor

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain