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    GL50803_0017516 Cathepsin B [ Giardia intestinalis ]

    Gene ID: 5701951, updated on 17-May-2024

    Summary

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    Gene symbol
    GL50803_0017516
    Gene description
    Cathepsin B
    Locus tag
    GL50803_0017516
    See related
    GiardiaDB:GL50803_0017516; VEuPathDB:GL50803_0017516
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Giardia intestinalis (strain: WB C6, culture-collection: ATCC:50803)
    Lineage
    Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia
    Old locus tag
    GL50803_17516
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    Genomic context

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    See GL50803_0017516 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_051856.1 (1421079..1422005)

    Chromosome 1 - NC_051856.1Genomic Context describing neighboring genes Neighboring gene GARP-like protein 4 Neighboring gene Ankyrin repeat protein 1 Neighboring gene putative DNA-dependent ATPase Neighboring gene ATP-binding cassette protein 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_051856.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic minimalism in the early diverging intestinal parasite Giardia lamblia. Morrison HG, et al. Science, 2007 Sep 28. PMID 17901334
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cathepsin B

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_051856.1 Reference assembly

      Range
      1421079..1422005
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001708981.1 → XP_001709033.1  Cathepsin B [Giardia intestinalis]

      See identical proteins and their annotated locations for XP_001709033.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A8B6Q6, V6TJ48
      Conserved Domains (1) summary
      cd02620
      Location:76 → 296
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    Nucleotide Protein
    Heading Accession and Version

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