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    walK cell wall metabolism sensor histidine kinase WalK [ Staphylococcus lugdunensis ]

    Gene ID: 58090774, updated on 3-Mar-2024

    Summary

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    Gene symbol
    walK
    Gene description
    cell wall metabolism sensor histidine kinase WalK
    Locus tag
    AL499_RS06870
    Gene type
    protein coding
    Organism
    Staphylococcus lugdunensis (strain: FDAARGOS_141, nat-host: Homo sapiens, culture-collection: FDA:FDAARGOS_141)
    Lineage
    Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus
    Old locus tag
    AL499_06875
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    Genomic context

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    NZ_CP014022.1Genomic Context describing neighboring genes Neighboring gene tRNA-Asp Neighboring gene response regulator YycF Neighboring gene two-component system activity regulator YycH Neighboring gene two-component system regulatory protein YycI Neighboring gene polysaccharide intercellular adhesin biosynthesis/export protein IcaC Neighboring gene intercellular adhesin biosynthesis polysaccharide N-deacetylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP014022.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A vancomycin resistance-associated WalK(S221P) mutation attenuates the virulence of vancomycin-intermediate Staphylococcus aureus. Rao Y, et al. J Adv Res, 2022 Sep. PMID 36100324, Free PMC Article
    2. Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus. Monk IR, et al. Nat Commun, 2019 Jul 11. PMID 31296851, Free PMC Article
    3. New insights into the WalK/WalR (YycG/YycF) essential signal transduction pathway reveal a major role in controlling cell wall metabolism and biofilm formation in Staphylococcus aureus. Dubrac S, et al. J Bacteriol, 2007 Nov. PMID 17827301, Free PMC Article
    4. Whole-Genome Sequencing of Seven Strains of Staphylococcus lugdunensis Allows Identification of Mobile Genetic Elements. Argemi X, et al. Genome Biol Evol, 2017 May 1. PMID 28444231, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    cell wall metabolism sensor histidine kinase WalK
    WP_002461016.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP014022.1 Reference assembly

      Range
      1451434..1453257
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_002461016.1 MULTISPECIES: cell wall metabolism sensor histidine kinase WalK [Staphylococcus]

      See identical proteins and their annotated locations for WP_002461016.1

      UniProtKB/TrEMBL
      A0A133Q782, A0A853V3W5
      Conserved Domains (1) summary
      NF033092
      Location:8 → 597
      HK_WalK; cell wall metabolism sensor histidine kinase WalK
    Nucleotide Protein
    Heading Accession and Version