cadm3 cell adhesion molecule 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cadm3provided by ZNC
Official Full Name: cell adhesion molecule 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-060512-196
See related: Ensembl:ENSDARG00000057013 AllianceGenome:ZFIN:ZDB-GENE-060512-196
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:136589
Summary: Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in plasma membrane. Predicted to be active in presynaptic membrane. Is expressed in alar plate midbrain region; immature eye; nervous system; radial glial cell; and trigeminal placode. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease. Orthologous to human CADM3 (cell adhesion molecule 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (44044156..44183451, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (44195762..44330472, complement)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Homophilic interaction of cell adhesion molecule 3 coordinates retina neuroepithelial cell proliferation.
Title: Homophilic interaction of cell adhesion molecule 3 coordinates retina neuroepithelial cell proliferation.
Data show that cadm3 and cadm2a are expressed throughout the nervous system of larval stage zebrafish.
Title: Localization of Cadm2a and Cadm3 proteins during development of the zebrafish nervous system.

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:238390

Z1406 (e-PCR)
- UniSTS:34625

G45562 (e-PCR)
- UniSTS:106364

z30274 (e-PCR), detects polymorphism
- UniSTS:238775

G45110 (e-PCR)
- UniSTS:105912

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cell adhesion molecule 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.