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    DFL1 Auxin-responsive GH3 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835539, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DFL1
    Official Full Name
    Auxin-responsive GH3 family protein
    Primary source
    TAIR:AT5G54510
    Locus tag
    AT5G54510
    See related
    Araport:AT5G54510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DWARF IN LIGHT 1; F24B18.13; F24B18_13; GH3.6; Gretchen Hagen3.6
    Summary
    Encodes an IAA-amido synthase that conjugates Ala, Asp, Phe, and Trp to auxin. Lines overexpressing this gene accumulate IAA-ASP and are hypersensitive to several auxins. Identified as a dominant mutation that displays shorter hypocotyls in light grown plants when compared to wild type siblings. Protein is similar to auxin inducible gene from pea (GH3).
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    Genomic context

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    See DFL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (22130964..22133688, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pinoid-binding protein 1 Neighboring gene flavodoxin-like quinone reductase 1 Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene serine protease, putative (Protein of unknown function, DUF538)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DFL1, an auxin-responsive GH3 gene homologue, negatively regulates shoot cell elongation and lateral root formation, and positively regulates the light response of hypocotyl length. Nakazawa M, et al. Plant J, 2001 Jan. PMID 11169197
    2. Auxin controls Arabidopsis adventitious root initiation by regulating jasmonic acid homeostasis. Gutierrez L, et al. Plant Cell, 2012 Jun. PMID 22730403, Free PMC Article
    3. Characterization of an Arabidopsis enzyme family that conjugates amino acids to indole-3-acetic acid. Staswick PE, et al. Plant Cell, 2005 Feb. PMID 15659623, Free PMC Article
    4. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_124831.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables indole-3-acetic acid amido synthetase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within auxin-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within intracellular auxin homeostasis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to auxin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Auxin-responsive GH3 family protein
    NP_200262.1
    • DWARF IN LIGHT 1 (DFL1); FUNCTIONS IN: indole-3-acetic acid amido synthetase activity; INVOLVED IN: auxin homeostasis, response to auxin stimulus, auxin mediated signaling pathway, unidimensional cell growth; LOCATED IN: chloroplast, cytoplasm; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: GH3 auxin-responsive promoter (InterPro:IPR004993); BEST Arabidopsis thaliana protein match is: Auxin-responsive GH3 family protein (TAIR:AT4G27260.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22130964..22133688 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124831.3 → NP_200262.1  Auxin-responsive GH3 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200262.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VYV6, Q9LSQ4
      UniProtKB/TrEMBL
      A0A178UBG0, A0A384LDF8, A0A7G2FG42, B5X4Z8
      Conserved Domains (1) summary
      PLN02620
      Location:1 → 612
      PLN02620; indole-3-acetic acid-amido synthetase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LSQ4.1

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