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    ZAT6 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830313, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ZAT6
    Official Full Name
    6
    Primary source
    TAIR:AT5G04340
    Locus tag
    AT5G04340
    See related
    Araport:AT5G04340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtZAT6; C2H2; C2H2 ZINC FINGER TRANSCRIPTION FACTOR; COLD INDUCED ZINC FINGER PROTEIN 2; CZF2; T19N18.70; T19N18_70; zinc finger of Arabidopsis thaliana 6
    Summary
    putative c2h2 zinc finger transcription factor mRNA
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    Genomic context

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    See ZAT6 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (1216058..1217362, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Pectin lyase-like superfamily protein Neighboring gene Shugoshin C terminus Neighboring gene Cytochrome P450 superfamily protein Neighboring gene Plant self-incompatibility protein S1 family Neighboring gene Plant self-incompatibility protein S1 family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Zinc-Finger Transcription Factor ZAT6 Positively Regulates Cadmium Tolerance through the Glutathione-Dependent Pathway in Arabidopsis. Chen J, et al. Plant Physiol, 2016 May. PMID 26983992, Free PMC Article
    2. Phosphate homeostasis and root development in Arabidopsis are synchronized by the zinc finger transcription factor ZAT6. Devaiah BN, et al. Plant Physiol, 2007 Sep. PMID 17631527, Free PMC Article
    3. Phosphorylation of the zinc finger transcriptional regulator ZAT6 by MPK6 regulates Arabidopsis seed germination under salt and osmotic stress. Liu XM, et al. Biochem Biophys Res Commun, 2013 Jan 18. PMID 23257164
    4. Zinc finger of Arabidopsis thaliana 6 is involved in melatonin-mediated auxin signaling through interacting INDETERMINATE DOMAIN15 and INDOLE-3-ACETIC ACID 17. Shi H, et al. J Pineal Res, 2018 Sep. PMID 29607541
    5. C2H2 zinc finger-SET histone methyltransferase is a plant-specific chromatin modifier. Krichevsky A, et al. Dev Biol, 2007 Mar 1. PMID 17224141, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. melatonin and auxin mediated the transcriptional levels of zinc finger of Arabidopsis thaliana (ZAT6) in a mutually antagonistic manner. ZAT6 negatively modulated the endogenous auxin level
      Title: Zinc finger of Arabidopsis thaliana 6 is involved in melatonin-mediated auxin signaling through interacting INDETERMINATE DOMAIN15 and INDOLE-3-ACETIC ACID 17.
    2. ZAT6 coordinately activates phytochelatin synthesis-related gene expression and directly targets GSH1 to positively regulate Cd accumulation and tolerance in Arabidopsis.
      Title: Zinc-Finger Transcription Factor ZAT6 Positively Regulates Cadmium Tolerance through the Glutathione-Dependent Pathway in Arabidopsis.
    3. these results suggest that phosphorylation by MPK6 is required for the functional role of ZAT6 in seed germination under salt and osmotic stress.
      Title: Phosphorylation of the zinc finger transcriptional regulator ZAT6 by MPK6 regulates Arabidopsis seed germination under salt and osmotic stress.
    4. repressor of primary root growth and regulates phosphate homeostasis through the control of root architecture
      Title: Phosphate homeostasis and root development in Arabidopsis are synchronized by the zinc finger transcription factor ZAT6.
    5. AtSWP1 and AtCZS (a C2H2 zinc finger-SET domain protein) represent two main components of a co-repressor complex that fine tunes flowering and is unique to plants.
      Title: C2H2 zinc finger-SET histone methyltransferase is a plant-specific chromatin modifier.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_120516.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription corepressor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    involved_in phosphate ion homeostasis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of root development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    6
    NP_196054.1
    • zinc finger of Arabidopsis thaliana 6 (ZAT6); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity, zinc ion binding, nucleic acid binding; LOCATED IN: intracellular; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Zinc finger, C2H2-type (InterPro:IPR007087); BEST Arabidopsis thaliana protein match is: salt tolerance zinc finger (TAIR:AT1G27730.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1216058..1217362 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120516.4 → NP_196054.1  6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196054.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22533, Q8GWG1
      UniProtKB/TrEMBL
      A0A178UKV2, A0A5S9Y1B1, A0A654FYM4
      Conserved Domains (1) summary
      pfam13912
      Location:88 → 114
      zf-C2H2_6; C2H2-type zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22533.1

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