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    APT3 adenine phosphoribosyl transferase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828353, updated on 18-Sep-2024

    Summary

    Official Symbol
    APT3
    Official Full Name
    adenine phosphoribosyl transferase 3
    Primary source
    TAIR:AT4G22570
    Locus tag
    AT4G22570
    See related
    Araport:AT4G22570
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    adenine phosphoribosyl transferase 3; F7K2.150; F7K2_150
    Summary
    Encodes an adenine phosphoribosyltransferase (APT; EC 2.4.2.7), which is a constitutively expressed enzyme involved in the one-step salvage of adenine to AMP. APT3 has higher affinity for zeatin, isopentenyladenine and benzyladenine than APT1 but lower Vmax than APT1.
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    Genomic context

    See APT3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (11882066..11885533, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Phosphatidic acid phosphatase (PAP2) family protein Neighboring gene sulfated surface-like glycoprotein Neighboring gene Exostosin family protein Neighboring gene ncRNA

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001341554.1
    NM_118383.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables adenine phosphoribosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in AMP salvage IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within adenine salvage TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
     
    located_in cytosol HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    adenine phosphoribosyl transferase 3
    NP_193988.1
    • adenine phosphoribosyl transferase 3 (APT3); CONTAINS InterPro DOMAIN/s: Adenine phosphoribosyl transferase (InterPro:IPR005764), Phosphoribosyltransferase (InterPro:IPR000836); BEST Arabidopsis thaliana protein match is: adenine phosphoribosyl transferase 4 (TAIR:AT4G12440.2); Has 8946 Blast hits to 8945 proteins in 2488 species: Archae - 280; Bacteria - 6058; Metazoa - 171; Fungi - 181; Plants - 166; Viruses - 0; Other Eukaryotes - 2090 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      11882066..11885533 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118383.4NP_193988.1  adenine phosphoribosyl transferase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193988.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LG17, Q9SUW2
      UniProtKB/TrEMBL
      A0A178V1I0, A0A5S9XVQ8, A0A7G2F048
      Conserved Domains (1) summary
      PLN02293
      Location:1183
      PLN02293; adenine phosphoribosyltransferase
    2. NM_001341554.1NP_001329095.1  adenine phosphoribosyl transferase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B6N4