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    GH3.17 Auxin-responsive GH3 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839706, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GH3.17
    Official Full Name
    Auxin-responsive GH3 family protein
    Primary source
    TAIR:AT1G28130
    Locus tag
    AT1G28130
    See related
    Araport:AT1G28130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F3H9.21; F3H9_21
    Summary
    encodes an IAA-amido synthase that conjugates Asp and other amino acids to auxin in vitro. Lines carrying insertions in this gene are hypersensitive to auxin.
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    Genomic context

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    See GH3.17 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (9825169..9828118)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene serine carboxypeptidase-like 45 Neighboring gene ubiquitin thioesterase otubain-like protein Neighboring gene uncharacterized protein Neighboring gene miscRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Local conjugation of auxin by the GH3 amido synthetases is required for normal development of roots and flowers in Arabidopsis. Guo R, et al. Biochem Biophys Res Commun, 2022 Jan 22. PMID 34883285
    2. Characterization of an Arabidopsis enzyme family that conjugates amino acids to indole-3-acetic acid. Staswick PE, et al. Plant Cell, 2005 Feb. PMID 15659623, Free PMC Article
    3. High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions. Koroleva OA, et al. Plant J, 2005 Jan. PMID 15610358
    4. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Local conjugation of auxin by the GH3 amido synthetases is required for normal development of roots and flowers in Arabidopsis.
      Title: Local conjugation of auxin by the GH3 amido synthetases is required for normal development of roots and flowers in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_102578.4
    NM_179387.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables indole-3-acetic acid amido synthetase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular auxin homeostasis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to auxin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Auxin-responsive GH3 family protein
    NP_174134.1
    • GH3.17; CONTAINS InterPro DOMAIN/s: GH3 auxin-responsive promoter (InterPro:IPR004993); BEST Arabidopsis thaliana protein match is: Auxin-responsive GH3 family protein (TAIR:AT5G54510.1); Has 1405 Blast hits to 1296 proteins in 239 species: Archae - 0; Bacteria - 491; Metazoa - 54; Fungi - 2; Plants - 672; Viruses - 0; Other Eukaryotes - 186 (source: NCBI BLink).
    NP_849718.1
    • GH3.17; CONTAINS InterPro DOMAIN/s: GH3 auxin-responsive promoter (InterPro:IPR004993); BEST Arabidopsis thaliana protein match is: Auxin-responsive GH3 family protein (TAIR:AT5G54510.1); Has 1092 Blast hits to 1087 proteins in 203 species: Archae - 0; Bacteria - 311; Metazoa - 52; Fungi - 2; Plants - 653; Viruses - 0; Other Eukaryotes - 74 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      9825169..9828118
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102578.4 → NP_174134.1  Auxin-responsive GH3 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174134.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FZ87
      UniProtKB/TrEMBL
      A0A178WH43, A0A5S9W5S6
      Conserved Domains (1) summary
      PLN02247
      Location:1 → 609
      PLN02247; indole-3-acetic acid-amido synthetase

    2. NM_179387.2 → NP_849718.1  Auxin-responsive GH3 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849718.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FZ87
      Conserved Domains (2) summary
      cl21606
      Location:1 → 466
      PLN02247; indole-3-acetic acid-amido synthetase
      pfam03321
      Location:1 → 436
      GH3; GH3 auxin-responsive promoter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FZ87.1

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