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    Spatc1l spermatogenesis and centriole associated 1-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499418, updated on 9-Dec-2024

    Summary

    Symbol
    Spatc1lprovided by RGD
    Full Name
    spermatogenesis and centriole associated 1-likeprovided by RGD
    Primary source
    RGD:1562578
    See related
    EnsemblRapid:ENSRNOG00000054549 AllianceGenome:RGD:1562578
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable identical protein binding activity and protein kinase A regulatory subunit binding activity. Predicted to be involved in spermatogenesis. Predicted to act upstream of or within actin polymerization or depolymerization; positive regulation of cAMP-dependent protein kinase activity; and positive regulation of cAMP/PKA signal transduction. Predicted to be active in centrosome and sperm head-tail coupling apparatus. Orthologous to human SPATC1L (spermatogenesis and centriole associated 1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 93.1) See more
    Orthologs
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    Genomic context

    See Spatc1l in Genome Data Viewer
    Location:
    20p12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (12073542..12082866, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (12074040..12083873, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (12825789..12835007, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene collagen type VI alpha 2 chain Neighboring gene formimidoyltransferase cyclodeaminase Neighboring gene uncharacterized LOC134483885 Neighboring gene lanosterol synthase Neighboring gene minichromosome maintenance complex component 3 associated protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase A regulatory subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase A regulatory subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in sperm head-tail coupling apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in sperm head-tail coupling apparatus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024296.1NP_001019467.1  speriolin-like protein

      See identical proteins and their annotated locations for NP_001019467.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079291
      UniProtKB/TrEMBL
      A0A8I5Y6R1, M0R8Y9, Q68FV7
      Related
      ENSRNOP00000077795.2, ENSRNOT00000102485.2
      Conserved Domains (2) summary
      pfam15058
      Location:5155
      Speriolin_N; Speriolin N-terminus
      pfam15059
      Location:197342
      Speriolin_C; Speriolin C-terminus

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      12073542..12082866 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279459.1XP_063135529.1  speriolin-like protein isoform X1

      UniProtKB/TrEMBL
      A6JKC5