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    STK4 serine/threonine kinase 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717730, updated on 17-Aug-2024

    Summary

    Official Symbol
    STK4provided by VGNC
    Official Full Name
    serine/threonine kinase 4provided by VGNC
    Primary source
    VGNC:VGNC:81588
    Locus tag
    EGK_02376
    See related
    Ensembl:ENSMMUG00000013212
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See STK4 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (80201234..80315073)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (19384578..19497854, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta Neighboring gene poly(A) binding protein cytoplasmic 1 like Neighboring gene translocase of outer mitochondrial membrane 34 Neighboring gene potassium voltage-gated channel modifier subfamily S member 1 Neighboring gene WAP four-disulfide core domain 5 Neighboring gene WAP four-disulfide core domain 12

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in protein tetramerization IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/threonine-protein kinase 4
    NP_001162148.1
    XP_015004349.2
    XP_015004351.2
    XP_028683260.1
    XP_028683261.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168677.1NP_001162148.1  serine/threonine-protein kinase 4

      See identical proteins and their annotated locations for NP_001162148.1

      Status: PROVISIONAL

      Source sequence(s)
      DP000043
      UniProtKB/Swiss-Prot
      A4K2T0
      UniProtKB/TrEMBL
      A0A1D5Q8L4, F6XFA0, G7N4R5
      Related
      ENSMMUP00000017358.4, ENSMMUT00000018534.4
      Conserved Domains (3) summary
      cd06612
      Location:26281
      STKc_MST1_2; Catalytic domain of the Serine/Threonine Kinases, Mammalian STe20-like protein kinase 1 and 2
      smart00220
      Location:30281
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam11629
      Location:433480
      Mst1_SARAH; C terminal SARAH domain of Mst1

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      80201234..80315073
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015148865.2XP_015004351.2  serine/threonine-protein kinase 4 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q8L4
      Conserved Domains (2) summary
      cd06612
      Location:1205
      STKc_MST1_2; Catalytic domain of the Serine/Threonine Kinases, Mammalian STe20-like protein kinase 1 and 2
      pfam11629
      Location:357404
      Mst1_SARAH; C terminal SARAH domain of Mst1
    2. XM_028827428.1XP_028683261.1  serine/threonine-protein kinase 4 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q8L4
      Conserved Domains (1) summary
      cd06612
      Location:26281
      STKc_MST1_2; Catalytic domain of the Serine/Threonine Kinases, Mammalian STe20-like protein kinase 1 and 2
    3. XM_015148863.2XP_015004349.2  serine/threonine-protein kinase 4 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q8L4
      Conserved Domains (2) summary
      cd06612
      Location:1205
      STKc_MST1_2; Catalytic domain of the Serine/Threonine Kinases, Mammalian STe20-like protein kinase 1 and 2
      pfam11629
      Location:357404
      Mst1_SARAH; C terminal SARAH domain of Mst1
    4. XM_028827427.1XP_028683260.1  serine/threonine-protein kinase 4 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q8L4
      Conserved Domains (2) summary
      cd06612
      Location:1205
      STKc_MST1_2; Catalytic domain of the Serine/Threonine Kinases, Mammalian STe20-like protein kinase 1 and 2
      pfam11629
      Location:357404
      Mst1_SARAH; C terminal SARAH domain of Mst1