Or2y1g olfactory receptor family 2 subfamily Y member 1G [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Or2y1gprovided by MGI
Official Full Name: olfactory receptor family 2 subfamily Y member 1Gprovided by MGI
Primary source: MGI:MGI:3031227
See related: Ensembl:ENSMUSG00000059864 AllianceGenome:MGI:3031227
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Olfr1393; MOR256-24
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 11 B1.2; 11 29.31 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (49154700..49183186)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (49263873..49292359)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model.
Title: Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model.
Renal Olfr1393 can contribute to the progression of type 2 diabetes, likely as a regulator of Na(+)-glucose cotransport in the proximal tubule.
Title: Renal olfactory receptor 1393 contributes to the progression of type 2 diabetes in a diet-induced obesity model.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1) 1 citation

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	ISA Inferred from Sequence Alignment more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	ISA Inferred from Sequence Alignment more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of smell	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within sensory perception of smell	ISA Inferred from Sequence Alignment more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	ISA Inferred from Sequence Alignment more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: olfactory receptor family 2 subfamily Y member 1G

Names: GA_x6K02T2QP88-6154577-6153642; MOR256-67_i; olfactory receptor 1393; olfactory receptor MOR256-24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_146471.1 → NP_666682.1 olfactory receptor family 2 subfamily Y member 1G

See identical proteins and their annotated locations for NP_666682.1

Status: PROVISIONAL

Source sequence(s)

AY073627

Consensus CDS

CCDS24603.1

UniProtKB/TrEMBL

Q8VFA7

Related

ENSMUSP00000077962.2, ENSMUST00000078932.2

Conserved Domains (2) summary

pfam00001
Location:41 → 289

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:35 → 304

7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000077.7 Reference GRCm39 C57BL/6J

Range

49154700..49183186

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030246013.1 → XP_030101873.1 olfactory receptor family 2 subfamily Y member 1G isoform X2

Conserved Domains (1) summary

cd15947
Location:8 → 249

7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_017314558.2 → XP_017170047.1 olfactory receptor family 2 subfamily Y member 1G isoform X1

Conserved Domains (1) summary

cd15947
Location:7 → 257

7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_006533360.3 → XP_006533423.1 olfactory receptor family 2 subfamily Y member 1G isoform X1

See identical proteins and their annotated locations for XP_006533423.1

Conserved Domains (1) summary

cd15947
Location:7 → 257

7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_017314560.2 → XP_017170049.1 olfactory receptor family 2 subfamily Y member 1G isoform X2

Conserved Domains (1) summary

cd15947
Location:8 → 249

7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_030246012.1 → XP_030101872.1 olfactory receptor family 2 subfamily Y member 1G isoform X1

Conserved Domains (1) summary

cd15947
Location:7 → 257

7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_030246011.1 → XP_030101871.1 olfactory receptor family 2 subfamily Y member 1G isoform X1

Conserved Domains (1) summary

cd15947
Location:7 → 257

7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
XM_017314559.2 → XP_017170048.1 olfactory receptor family 2 subfamily Y member 1G isoform X1

Conserved Domains (1) summary

cd15947
Location:7 → 257

7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors