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    ddx54.L DEAD-box helicase 54 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 495097, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ddx54.L
    Official Full Name
    DEAD-box helicase 54 L homeolog
    Primary source
    Xenbase:XB-GENE-1011581
    Locus tag
    XELAEV_18007432mg
    See related
    EnsemblRapid:ENSXLAG00005016440 AllianceGenome:Xenbase:XB-GENE-1011581
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    ddx54
    Summary
    Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be located in cytoplasm and nucleolus. Orthologous to human DDX54 (DEAD-box helicase 54). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See ddx54.L in Genome Data Viewer
    Location:
    chromosome: 1L
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (157108055..157121433, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (144140310..144153689, complement)

    Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121394540 Neighboring gene coiled-coil domain-containing protein 42 like-2-like Neighboring gene RBPJ interacting and tubulin associated 1 L homeolog Neighboring gene IQ motif containing D L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC132273

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DEAD-box helicase 54 L homeolog
    Names
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 54

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001094797.1 → NP_001088266.1  DEAD-box helicase 54 L homeolog

      See identical proteins and their annotated locations for NP_001088266.1

      Status: PROVISIONAL

      Source sequence(s)
      BC108844
      UniProtKB/TrEMBL
      A0A974E0Q5, Q2VPF9, Q5XH08
      Related
      ENSXLAP00005048434.1, ENSXLAT00005049549.1
      Conserved Domains (4) summary
      PRK01297
      Location:29 → 441
      PRK01297; ATP-dependent RNA helicase RhlB; Provisional
      cd00079
      Location:300 → 420
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      cd00268
      Location:77 → 279
      DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
      pfam08147
      Location:679 → 739
      DBP10CT; DBP10CT (NUC160) domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      157108055..157121433 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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