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    RasGAP1 Ras GTPase activating protein 1 [ Apis mellifera (honey bee) ]

    Gene ID: 412003, updated on 2-Oct-2024

    Summary

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    Gene symbol
    RasGAP1
    Gene description
    Ras GTPase activating protein 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Apis mellifera
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea; Anthophila; Apidae; Apis
    Also known as
    Rasa3; GB41592
    Orthologs
    fruit fly all
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    Genomic context

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    See RasGAP1 in Genome Data Viewer
    Location:
    chromosome: LG2
    Exon count:
    18
    Annotation release Status Assembly LG Location
    104 current Amel_HAv3.1 (GCF_003254395.2) LG2 NC_037639.1 (131861..145713, complement)
    103 previous assembly Amel_4.5 (GCF_000002195.4) Unplaced Scaffold NW_003378246.1 (102311..109969)

    Linkage Group LG2 - NC_037639.1Genomic Context describing neighboring genes Neighboring gene male-specific lethal 2 Neighboring gene U2 snRNP-associated SURP motif-containing protein Neighboring gene putative SERF-like protein Neighboring gene glucose-6-phosphate 1-epimerase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Differential expression of endogenous plant cell wall degrading enzyme genes in the stick insect (Phasmatodea) midgut. Shelomi M, et al. BMC Genomics, 2014 Oct 21. PMID 25331961, Free PMC Article
    2. Insights into social insects from the genome of the honeybee Apis mellifera. Honeybee Genome Sequencing Consortium. Nature, 2006 Oct 26. PMID 17073008, Free PMC Article
    3. ProtoBee: hierarchical classification and annotation of the honey bee proteome. Kaplan N, et al. Genome Res, 2006 Nov. PMID 17065614, Free PMC Article
    4. Finding the missing honey bee genes: lessons learned from a genome upgrade. Elsik CG, et al. BMC Genomics, 2014 Jan 30. PMID 24479613, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GTPase-activating protein; ras GTPase-activating protein 3
    Names
    RAS p21 protein activator 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Apis mellifera Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Amel_HAv3.1 Primary Assembly

    Genomic

    1. NC_037639.1 Reference Amel_HAv3.1 Primary Assembly

      Range
      131861..145713 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_026438970.1 → XP_026294755.1  GTPase-activating protein isoform X4

      UniProtKB/TrEMBL
      A0A7M7L862, A0A8B8GSS2
      Conserved Domains (5) summary
      smart00107
      Location:714 → 749
      BTK; Bruton's tyrosine kinase Cys-rich motif
      cd04010
      Location:145 → 300
      C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
      cd05128
      Location:311 → 579
      RasGAP_GAP1_like; Ras-GTPase Activating Domain of GAP1 and similar proteins
      cd01244
      Location:614 → 719
      PH_GAP1-like; RAS p21 protein activator (GTPase activating protein) family pleckstrin homology (PH) domain
      cl14603
      Location:14 → 135
      C2; C2 domain

    2. XM_026438967.1 → XP_026294752.1  ras GTPase-activating protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A7M7KYW5, A0A8B8GSW2
      Conserved Domains (5) summary
      smart00107
      Location:700 → 735
      BTK; Bruton's tyrosine kinase Cys-rich motif
      cd04010
      Location:145 → 300
      C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
      cd05128
      Location:311 → 579
      RasGAP_GAP1_like; Ras-GTPase Activating Domain of GAP1 and similar proteins
      cd01244
      Location:600 → 705
      PH_GAP1-like; RAS p21 protein activator (GTPase activating protein) family pleckstrin homology (PH) domain
      cl14603
      Location:14 → 135
      C2; C2 domain

    3. XM_006572017.3 → XP_006572080.2  ras GTPase-activating protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A7M7H2F9, A0A8B6ZAA0
      Conserved Domains (5) summary
      smart00107
      Location:714 → 749
      BTK; Bruton's tyrosine kinase Cys-rich motif
      cd04010
      Location:145 → 300
      C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
      cd05128
      Location:311 → 579
      RasGAP_GAP1_like; Ras-GTPase Activating Domain of GAP1 and similar proteins
      cd01244
      Location:614 → 719
      PH_GAP1-like; RAS p21 protein activator (GTPase activating protein) family pleckstrin homology (PH) domain
      cl14603
      Location:14 → 135
      C2; C2 domain

    4. XM_026438968.1 → XP_026294753.1  GTPase-activating protein isoform X3

      UniProtKB/TrEMBL
      A0A7M7L422, A0A7M7MK26, A0A8B8GU35, A0A8B8GV09
      Conserved Domains (5) summary
      smart00107
      Location:661 → 696
      BTK; Bruton's tyrosine kinase Cys-rich motif
      cd04010
      Location:92 → 247
      C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
      cd05128
      Location:258 → 526
      RasGAP_GAP1_like; Ras-GTPase Activating Domain of GAP1 and similar proteins
      cd01244
      Location:561 → 666
      PH_GAP1-like; RAS p21 protein activator (GTPase activating protein) family pleckstrin homology (PH) domain
      cl14603
      Location:2 → 82
      C2; C2 domain

    5. XM_026438969.1 → XP_026294754.1  GTPase-activating protein isoform X3

      UniProtKB/TrEMBL
      A0A7M7L422, A0A7M7MK26, A0A8B8GU35, A0A8B8GV09
      Conserved Domains (5) summary
      smart00107
      Location:661 → 696
      BTK; Bruton's tyrosine kinase Cys-rich motif
      cd04010
      Location:92 → 247
      C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
      cd05128
      Location:258 → 526
      RasGAP_GAP1_like; Ras-GTPase Activating Domain of GAP1 and similar proteins
      cd01244
      Location:561 → 666
      PH_GAP1-like; RAS p21 protein activator (GTPase activating protein) family pleckstrin homology (PH) domain
      cl14603
      Location:2 → 82
      C2; C2 domain
    Nucleotide Protein Strain
    Heading Accession and Version

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