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    SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 [ Pteropus alecto (black flying fox) ]

    Gene ID: 102890092, updated on 30-Mar-2024

    Summary

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    Gene symbol
    SRGAP3
    Gene description
    SLIT-ROBO Rho GTPase activating protein 3
    Locus tag
    PAL_GLEAN10022252
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pteropus alecto
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
    Orthologs
    human mouse all
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    Genomic context

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    See SRGAP3 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    102 current ASM32557v1 (GCF_000325575.1) Unplaced Scaffold NW_006440638.1 (28754972..28878508, complement)

    NW_006440638.1Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene RAD18 E3 ubiquitin protein ligase Neighboring gene 5S ribosomal RNA Neighboring gene 5S ribosomal RNA Neighboring gene MARCKS-related protein-like Neighboring gene 40S ribosomal protein S29 pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_006440638 Unplaced Scaffold Reference ASM32557v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: SLIT-ROBO Rho GTPase-activating protein 3
    Names
    SLIT-ROBO Rho GTPase-activating protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Pteropus alecto Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM32557v1 Primary Assembly

    Genomic

    1. NW_006440638.1 Reference ASM32557v1 Primary Assembly

      Range
      28754972..28878508 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025050863.1 → XP_024906631.1  LOW QUALITY PROTEIN: SLIT-ROBO Rho GTPase-activating protein 3

      UniProtKB/TrEMBL
      L5KBG9
      Conserved Domains (3) summary
      cd07684
      Location:33 → 285
      F-BAR_srGAP3; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 3
      cd11955
      Location:750 → 802
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:509 → 691
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
    Nucleotide Protein
    Heading Accession and Version

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