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    TIP3;1 Aquaporin-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843653, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TIP3;1
    Official Full Name
    Aquaporin-like superfamily protein
    Primary source
    TAIR:AT1G73190
    Locus tag
    AT1G73190
    See related
    Araport:AT1G73190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ALPHA-TIP; ALPHA-TONOPLAST INTRINSIC PROTEIN; T18K17.14; T18K17_14
    Summary
    Moves to the Protein Storage Vacuole in a Golgi independent manner
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    Genomic context

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    See TIP3;1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (27521944..27523332)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Eukaryotic translation initiation factor eIF2A family protein Neighboring gene bonsai Neighboring gene testis-expressed sequence 2-like protein (DUF2404) Neighboring gene hypothetical protein (DUF789) Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Vegetative and Seed-Specific Forms of Tonoplast Intrinsic Protein in the Vacuolar Membrane of Arabidopsis thaliana. Höfte H, et al. Plant Physiol, 1992 Jun. PMID 16668923, Free PMC Article
    2. Alpha tonoplast intrinsic protein is specifically associated with vacuole membrane involved in an autophagic process. Moriyasu Y, et al. Plant Cell Physiol, 2003 Aug. PMID 12941871
    3. Arabidopsis seed-specific vacuolar aquaporins are involved in maintaining seed longevity under the control of ABSCISIC ACID INSENSITIVE 3. Mao Z, et al. J Exp Bot, 2015 Aug. PMID 26019256, Free PMC Article
    4. A small molecule inhibitor partitions two distinct pathways for trafficking of tonoplast intrinsic proteins in Arabidopsis. Rivera-Serrano EE, et al. PLoS One, 2012. PMID 22957103, Free PMC Article
    5. Fluorescent reporter proteins for the tonoplast and the vacuolar lumen identify a single vacuolar compartment in Arabidopsis cells. Hunter PR, et al. Plant Physiol, 2007 Dec. PMID 17905861, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. TIP3;1 and TIP3;2 promoters could be activated by ABI3 in the presence of abscisic acid (ABA) in Arabidopsis protoplasts. TIP3 proteins were detected in protoplasts transiently expressing ABI3 and in ABI3-overexpressing seedlings treated with ABA.
      Title: Arabidopsis seed-specific vacuolar aquaporins are involved in maintaining seed longevity under the control of ABSCISIC ACID INSENSITIVE 3.
    2. unlike for TIP1;1, trafficking of markers for TIP3;1 and TIP2;1 is insensitive to Brefeldin A in Arabidopsis hypocotyls
      Title: A small molecule inhibitor partitions two distinct pathways for trafficking of tonoplast intrinsic proteins in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_105978.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables water channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within autophagy TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in central vacuole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in protein storage vacuole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Aquaporin-like superfamily protein
    NP_177462.1
    • TIP3;1; FUNCTIONS IN: water channel activity; INVOLVED IN: autophagy, transport; LOCATED IN: plant-type vacuole membrane, protein storage vacuole, membrane, central vacuole; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: seedling growth, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: beta-tonoplast intrinsic protein (TAIR:AT1G17810.1); Has 10625 Blast hits to 10599 proteins in 2166 species: Archae - 81; Bacteria - 4980; Metazoa - 1496; Fungi - 430; Plants - 2511; Viruses - 0; Other Eukaryotes - 1127 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27521944..27523332
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105978.4 → NP_177462.1  Aquaporin-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177462.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P26587
      UniProtKB/TrEMBL
      A0A178WAX2, A0A5S9WTZ2
      Conserved Domains (1) summary
      cl00200
      Location:11 → 268
      MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P26587.1

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