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    EXOSC10 exosome component 10 [ Myotis lucifugus (little brown bat) ]

    Gene ID: 102434136, updated on 11-Apr-2024

    Summary

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    Gene symbol
    EXOSC10
    Gene description
    exosome component 10
    See related
    Ensembl:ENSMLUG00000004276
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Myotis lucifugus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
    Orthologs
    human mouse all
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    Genomic context

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    See EXOSC10 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    102 current Myoluc2.0 (GCF_000147115.1) Unplaced Scaffold NW_005871549.1 (49287..71304, complement)

    NW_005871549.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111823462 Neighboring gene MBL associated serine protease 2 Neighboring gene spermidine synthase Neighboring gene mechanistic target of rapamycin kinase Neighboring gene U6 spliceosomal RNA Neighboring gene angiopoietin like 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_005871549 Unplaced Scaffold Reference Myoluc2.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3'-5'-RNA exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in TRAMP-dependent tRNA surveillance pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in histone mRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent CUT catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent antisense transcript catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent rRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent snRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear polyadenylation-dependent snoRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in poly(A)-dependent snoRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nuclear exosome (RNase complex) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    exosome component 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Myotis lucifugus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Myoluc2.0

    Genomic

    1. NW_005871549.1 Reference Myoluc2.0

      Range
      49287..71304 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023744958.1 → XP_023600726.1  exosome component 10 isoform X1

      Conserved Domains (3) summary
      cd06147
      Location:285 → 474
      Rrp6p_like_exo; DEDDy 3'-5' exonuclease domain of yeast Rrp6p, human polymyositis/scleroderma autoantigen 100kDa, and similar proteins
      smart00341
      Location:503 → 583
      HRDC; Helicase and RNase D C-terminal
      pfam08066
      Location:46 → 130
      PMC2NT; PMC2NT (NUC016) domain

    2. XM_023744959.1 → XP_023600727.1  exosome component 10 isoform X2

      Conserved Domains (3) summary
      cd06147
      Location:285 → 474
      Rrp6p_like_exo; DEDDy 3'-5' exonuclease domain of yeast Rrp6p, human polymyositis/scleroderma autoantigen 100kDa, and similar proteins
      smart00341
      Location:503 → 583
      HRDC; Helicase and RNase D C-terminal
      pfam08066
      Location:46 → 130
      PMC2NT; PMC2NT (NUC016) domain

    3. XM_006103714.3 → XP_006103776.1  exosome component 10 isoform X3

      UniProtKB/TrEMBL
      G1P226
      Related
      ENSMLUP00000003902.2, ENSMLUT00000004285.2
      Conserved Domains (4) summary
      cd06147
      Location:285 → 474
      Rrp6p_like_exo; DEDDy 3'-5' exonuclease domain of yeast Rrp6p, human polymyositis/scleroderma autoantigen 100kDa, and similar proteins
      smart00341
      Location:503 → 583
      HRDC; Helicase and RNase D C-terminal
      pfam05466
      Location:737 → 849
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
      pfam08066
      Location:46 → 132
      PMC2NT; PMC2NT (NUC016) domain

    4. XM_014446095.2 → XP_014301581.1  exosome component 10 isoform X4

      Conserved Domains (3) summary
      cd06147
      Location:285 → 474
      Rrp6p_like_exo; DEDDy 3'-5' exonuclease domain of yeast Rrp6p, human polymyositis/scleroderma autoantigen 100kDa, and similar proteins
      smart00341
      Location:503 → 583
      HRDC; Helicase and RNase D C-terminal
      pfam08066
      Location:46 → 132
      PMC2NT; PMC2NT (NUC016) domain
    Nucleotide Protein
    Heading Accession and Version

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