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    CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100444432, updated on 3-Dec-2024

    Summary

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    Gene symbol
    CACNB4
    Gene description
    calcium voltage-gated channel auxiliary subunit beta 4
    Locus tag
    CR201_G0021855
    See related
    Ensembl:ENSPPYG00000012849
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Orthologs
    human mouse all
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    Genomic context

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    See CACNB4 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 11 NC_071996.2 (54251925..54524052, complement)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 2B NC_071987.1 (51603100..51867624, complement)

    Chromosome 11 - NC_071996.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134759595 Neighboring gene nebulin Neighboring gene ARF like GTPase 5A Neighboring gene uncharacterized LOC129057835 Neighboring gene large ribosomal subunit protein eL30-like Neighboring gene uncharacterized LOC134759597 Neighboring gene signal transducing adaptor molecule 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of voltage-gated calcium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    voltage-dependent L-type calcium channel subunit beta-4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071996.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      54251925..54524052 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009237708.4 → XP_009235983.2  voltage-dependent L-type calcium channel subunit beta-4 isoform X2

      UniProtKB/TrEMBL
      A0A2J8V7C4, A0A2J8V7D6, A0A8I5YQG2, H2P7J8
      Related
      ENSPPYP00000033193.1
      Conserved Domains (3) summary
      cd12043
      Location:91 → 158
      SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
      pfam00625
      Location:218 → 398
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:50 → 91
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

    2. XM_063712804.1 → XP_063568874.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X1

      UniProtKB/TrEMBL
      A0A2J8V7D6, H2P7J8

    3. XM_009237707.4 → XP_009235982.2  voltage-dependent L-type calcium channel subunit beta-4 isoform X3

      UniProtKB/TrEMBL
      A0A2J8V7A7, A0A2J8V7D6, A0A8I5UY40, H2P7J8
      Related
      ENSPPYP00000044048.1
      Conserved Domains (3) summary
      cd12043
      Location:73 → 140
      SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
      pfam00625
      Location:200 → 380
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:32 → 73
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

    4. XM_002812483.5 → XP_002812529.2  voltage-dependent L-type calcium channel subunit beta-4 isoform X4

      See identical proteins and their annotated locations for XP_002812529.2

      UniProtKB/TrEMBL
      A0A2J8V7C6, A0A2J8V7D3, A0A2J8V7F0, K7EVB5
      Related
      ENSPPYP00000024497.2
      Conserved Domains (3) summary
      cd12043
      Location:57 → 124
      SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
      pfam00625
      Location:184 → 364
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:16 → 57
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

    5. XM_024243842.3 → XP_024099610.1  voltage-dependent L-type calcium channel subunit beta-4 isoform X5

      UniProtKB/TrEMBL
      A0A2J8V7D6, A0A6D2X8X9, H2P7J8
      Conserved Domains (3) summary
      cd12043
      Location:44 → 111
      SH3_CACNB4; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta4
      pfam00625
      Location:171 → 351
      Guanylate_kin; Guanylate kinase
      pfam12052
      Location:3 → 44
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

    6. XM_054548872.2 → XP_054404847.2  voltage-dependent L-type calcium channel subunit beta-4 isoform X6

    Nucleotide Protein
    Heading Accession and Version

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