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    CHRNE cholinergic receptor nicotinic epsilon subunit [ Pan troglodytes (chimpanzee) ]

    Gene ID: 468165, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CHRNEprovided by VGNC
    Official Full Name
    cholinergic receptor nicotinic epsilon subunitprovided by VGNC
    Primary source
    VGNC:VGNC:12052
    Locus tag
    CK820_G0036929
    See related
    Ensembl:ENSPTRG00000008612
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See CHRNE in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (15413723..15427023, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (13653219..13667322, complement)

    Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene phospholipase D2 Neighboring gene misshapen like kinase 1 Neighboring gene chromosome 17 C17orf107 homolog Neighboring gene solute carrier family 25 member 11 Neighboring gene glycoprotein Ib platelet subunit alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetylcholine-gated monoatomic cation-selective channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acetylcholine receptor subunit epsilon
    Names
    cholinergic receptor, nicotinic, epsilon (muscle)
    nicotinic acetylcholine receptor epsilon polypeptide

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      15413723..15427023 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016931303.3 → XP_016786792.1  acetylcholine receptor subunit epsilon isoform X2

    2. XM_016931304.3 → XP_016786793.1  acetylcholine receptor subunit epsilon isoform X3

    3. XM_016931302.3 → XP_016786791.1  acetylcholine receptor subunit epsilon isoform X1

      UniProtKB/TrEMBL
      A0A2J8KQN2, A0A6D2WYY7, H2QBZ0
      Related
      ENSPTRP00000014702.4
      Conserved Domains (2) summary
      pfam02931
      Location:24 → 240
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam02932
      Location:247 → 474
      Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
    Nucleotide Protein
    Heading Accession and Version

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