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    LOC102233692 caskin-2 [ Xiphophorus maculatus (southern platyfish) ]

    Gene ID: 102233692, updated on 22-Oct-2023

    Summary

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    Gene symbol
    LOC102233692
    Gene description
    caskin-2
    See related
    Ensembl:ENSXMAG00000011568
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xiphophorus maculatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
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    Genomic context

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    See LOC102233692 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    102 current X_maculatus-5.0-male (GCF_002775205.1) 10 NC_036452.1 (18416052..18472629, complement)
    101 previous assembly Xiphophorus_maculatus-4.4.2 (GCF_000241075.1) Unplaced Scaffold NW_005372467.1 (126029..149185, complement)

    Chromosome 10 - NC_036452.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102233173 Neighboring gene ras-related protein Rab-37-like Neighboring gene SLC9A3 regulator 1 Neighboring gene methyltransferase 9, His-X-His N1-histidine Neighboring gene KDEL endoplasmic reticulum protein retention receptor 2b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    caskin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xiphophorus maculatus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference X_maculatus-5.0-male Primary Assembly

    Genomic

    1. NC_036452.1 Reference X_maculatus-5.0-male Primary Assembly

      Range
      18416052..18472629 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023341116.1 → XP_023196884.1  caskin-2 isoform X2

      UniProtKB/TrEMBL
      A0A3B5Q8U2
      Conserved Domains (9) summary
      cd09497
      Location:511 → 576
      SAM_caskin1,2_repeat1; SAM domain of caskin protein repeat 1
      cd09498
      Location:577 → 647
      SAM_caskin1,2_repeat2; SAM domain of caskin protein repeat 2
      cd12063
      Location:291 → 352
      SH3_Caskin2; Src Homology 3 domain of CASK interacting protein 2
      cd00204
      Location:49 → 174
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:120 → 151
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:230 → 268
      Ank_4; Ankyrin repeats (many copies)
      pfam16600
      Location:413 → 450
      Caskin1-CID; Caskin1 CASK-interaction domain
      pfam16632
      Location:1441 → 1501
      Caskin-tail; C-terminal region of Caskin
      pfam16907
      Location:939 → 1027
      Caskin-Pro-rich; Proline rich region of Caskin proteins

    2. XM_014472882.2 → XP_014328368.1  caskin-2 isoform X5

      UniProtKB/TrEMBL
      A0A3B5Q8U2
      Conserved Domains (10) summary
      cd09497
      Location:423 → 488
      SAM_caskin1,2_repeat1; SAM domain of caskin protein repeat 1
      cd09498
      Location:489 → 559
      SAM_caskin1,2_repeat2; SAM domain of caskin protein repeat 2
      smart00454
      Location:422 → 484
      SAM; Sterile alpha motif
      cd12063
      Location:203 → 264
      SH3_Caskin2; Src Homology 3 domain of CASK interacting protein 2
      cd00204
      Location:27 → 160
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:70 → 170
      Ank_2; Ankyrin repeats (3 copies)
      pfam16600
      Location:325 → 359
      Caskin1-CID; Caskin1 CASK-interaction domain
      pfam16632
      Location:1353 → 1415
      Caskin-tail; C-terminal region of Caskin
      pfam16907
      Location:851 → 939
      Caskin-Pro-rich; Proline rich region of Caskin proteins
      sd00045
      Location:32 → 63
      ANK; ANK repeat [structural motif]

    3. XM_023341114.1 → XP_023196882.1  caskin-2 isoform X1

      UniProtKB/TrEMBL
      A0A3B5PVB4, A0A3B5Q8U2
      Conserved Domains (9) summary
      cd09497
      Location:511 → 576
      SAM_caskin1,2_repeat1; SAM domain of caskin protein repeat 1
      cd09498
      Location:577 → 647
      SAM_caskin1,2_repeat2; SAM domain of caskin protein repeat 2
      cd12063
      Location:291 → 352
      SH3_Caskin2; Src Homology 3 domain of CASK interacting protein 2
      cd00204
      Location:49 → 174
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:120 → 151
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:230 → 268
      Ank_4; Ankyrin repeats (many copies)
      pfam16600
      Location:413 → 450
      Caskin1-CID; Caskin1 CASK-interaction domain
      pfam16632
      Location:1441 → 1503
      Caskin-tail; C-terminal region of Caskin
      pfam16907
      Location:939 → 1027
      Caskin-Pro-rich; Proline rich region of Caskin proteins

    4. XM_023341118.1 → XP_023196886.1  caskin-2 isoform X4

      UniProtKB/TrEMBL
      A0A3B5Q8U2, M4AAX2
      Related
      ENSXMAP00000011616.2, ENSXMAT00000011630.2
      Conserved Domains (8) summary
      cd09497
      Location:444 → 509
      SAM_caskin1,2_repeat1; SAM domain of caskin protein repeat 1
      cd09498
      Location:510 → 580
      SAM_caskin1,2_repeat2; SAM domain of caskin protein repeat 2
      cd12063
      Location:291 → 352
      SH3_Caskin2; Src Homology 3 domain of CASK interacting protein 2
      cd00204
      Location:49 → 174
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:120 → 151
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:230 → 268
      Ank_4; Ankyrin repeats (many copies)
      pfam16632
      Location:1374 → 1436
      Caskin-tail; C-terminal region of Caskin
      pfam16907
      Location:872 → 960
      Caskin-Pro-rich; Proline rich region of Caskin proteins

    5. XM_023341117.1 → XP_023196885.1  caskin-2 isoform X3

      UniProtKB/TrEMBL
      A0A3B5Q8U2, A0A3B5QV16
      Related
      ENSXMAP00000034130.1, ENSXMAT00000031304.1
      Conserved Domains (8) summary
      cd09497
      Location:485 → 550
      SAM_caskin1,2_repeat1; SAM domain of caskin protein repeat 1
      cd09498
      Location:551 → 621
      SAM_caskin1,2_repeat2; SAM domain of caskin protein repeat 2
      cd12063
      Location:291 → 352
      SH3_Caskin2; Src Homology 3 domain of CASK interacting protein 2
      cd00204
      Location:49 → 174
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:120 → 151
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:230 → 268
      Ank_4; Ankyrin repeats (many copies)
      pfam16632
      Location:1415 → 1477
      Caskin-tail; C-terminal region of Caskin
      pfam16907
      Location:913 → 1001
      Caskin-Pro-rich; Proline rich region of Caskin proteins

    6. XM_023341115.1 → XP_023196883.1  caskin-2 isoform X1

      UniProtKB/TrEMBL
      A0A3B5PVB4, A0A3B5Q8U2
      Related
      ENSXMAP00000023603.1, ENSXMAT00000026870.1
      Conserved Domains (9) summary
      cd09497
      Location:511 → 576
      SAM_caskin1,2_repeat1; SAM domain of caskin protein repeat 1
      cd09498
      Location:577 → 647
      SAM_caskin1,2_repeat2; SAM domain of caskin protein repeat 2
      cd12063
      Location:291 → 352
      SH3_Caskin2; Src Homology 3 domain of CASK interacting protein 2
      cd00204
      Location:49 → 174
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:120 → 151
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:230 → 268
      Ank_4; Ankyrin repeats (many copies)
      pfam16600
      Location:413 → 450
      Caskin1-CID; Caskin1 CASK-interaction domain
      pfam16632
      Location:1441 → 1503
      Caskin-tail; C-terminal region of Caskin
      pfam16907
      Location:939 → 1027
      Caskin-Pro-rich; Proline rich region of Caskin proteins
    Nucleotide Protein Strain
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