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    LOC106467885 complement factor B-like [ Limulus polyphemus (Atlantic horseshoe crab) ]

    Gene ID: 106467885, updated on 21-Dec-2023

    Summary

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    Gene symbol
    LOC106467885
    Gene description
    complement factor B-like
    See related
    EnsemblRapid:LOC106467885
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Limulus polyphemus
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Merostomata; Xiphosura; Limulidae; Limulus
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    Genomic context

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    See LOC106467885 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    101 current Limulus_polyphemus-2.1.2 (GCF_000517525.1) Unplaced Scaffold NW_013668388.1 (134844..159774)

    NW_013668388.1Genomic Context describing neighboring genes Neighboring gene Down syndrome cell adhesion molecule-like protein Dscam2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_013668388 Unplaced Scaffold Reference Limulus_polyphemus-2.1.2 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in complement activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    complement factor B-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Limulus polyphemus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Limulus_polyphemus-2.1.2 Primary Assembly

    Genomic

    1. NW_013668388.1 Reference Limulus_polyphemus-2.1.2 Primary Assembly

      Range
      134844..159774
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022396097.1 → XP_022251805.1  complement factor B-like isoform X1

      Related
      XP_022251805.1, XM_022396097.1
      Conserved Domains (4) summary
      cd00033
      Location:81 → 136
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      smart00032
      Location:22 → 74
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      cd00190
      Location:478 → 671
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      cd00198
      Location:265 → 428
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    2. XM_013928269.2 → XP_013783723.2  complement factor B-like isoform X2

      Related
      XP_013783723.2, XM_013928269.2
      Conserved Domains (4) summary
      cd00033
      Location:81 → 136
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      smart00032
      Location:22 → 74
      CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
      cd00190
      Location:394 → 587
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      cd00198
      Location:181 → 344
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    Nucleotide Protein
    Heading Accession and Version

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