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    tnrc6c2 trinucleotide repeat containing adaptor 6C2 [ Danio rerio (zebrafish) ]

    Gene ID: 100149391, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tnrc6c2provided by ZNC
    Official Full Name
    trinucleotide repeat containing adaptor 6C2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061207-48
    See related
    Ensembl:ENSDARG00000103851 AllianceGenome:ZFIN:ZDB-GENE-061207-48
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-10p5.9
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in miRNA-mediated post-transcriptional gene silencing and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within regulation of translation. Predicted to be located in cytosol. Predicted to be active in P-body and nucleoplasm. Orthologous to human TNRC6C (trinucleotide repeat containing adaptor 6C). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See tnrc6c2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (18716291..18782385, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (22241523..22311656, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 207, b Neighboring gene rhomboid, veinlet-like 3 (Drosophila) Neighboring gene uncharacterized LOC137495951 Neighboring gene septin 9b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    trinucleotide repeat-containing gene 6C protein
    Names
    trinucleotide repeat containing 6C2
    trinucleotide repeat-containing gene 6C-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      18716291..18782385 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021477077.2 → XP_021332752.1  trinucleotide repeat-containing gene 6C protein isoform X2

      UniProtKB/TrEMBL
      A0A0R4IVQ1, A0A8M9PMP3
      Related
      ENSDARP00000141129.1, ENSDART00000171537.2
      Conserved Domains (4) summary
      cd12713
      Location:1351 → 1433
      RRM_TNRC6C; RNA recognition motif in vertebrate trinucleotide repeat-containing gene 6C protein (TNRC6C)
      cd14283
      Location:800 → 837
      UBA_TNR6C; UBA domain found in trinucleotide repeat-containing gene 6C protein (TNRC6C) and similar proteins
      pfam12938
      Location:880 → 1097
      M_domain; M domain of GW182
      pfam16608
      Location:1098 → 1350
      TNRC6-PABC_bdg; TNRC6-PABC binding domain

    2. XM_021477075.2 → XP_021332750.1  trinucleotide repeat-containing gene 6C protein isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q4I3
      Conserved Domains (4) summary
      cd12713
      Location:1388 → 1470
      RRM_TNRC6C; RNA recognition motif in vertebrate trinucleotide repeat-containing gene 6C protein (TNRC6C)
      cd14283
      Location:800 → 837
      UBA_TNR6C; UBA domain found in trinucleotide repeat-containing gene 6C protein (TNRC6C) and similar proteins
      pfam12938
      Location:880 → 1097
      M_domain; M domain of GW182
      pfam16608
      Location:1098 → 1387
      TNRC6-PABC_bdg; TNRC6-PABC binding domain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394637.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      241167..293535 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017356616.3 → XP_017212105.2  trinucleotide repeat-containing gene 6C protein isoform X2

      UniProtKB/TrEMBL
      A0A8M6YYV7
      Conserved Domains (5) summary
      cd12713
      Location:1351 → 1433
      RRM_TNRC6C; RNA recognition motif in vertebrate trinucleotide repeat-containing gene 6C protein (TNRC6C)
      cd14283
      Location:800 → 837
      UBA_TNR6C; UBA domain found in trinucleotide repeat-containing gene 6C protein (TNRC6C) and similar proteins
      pfam10427
      Location:670 → 803
      Ago_hook; Argonaute hook
      pfam12938
      Location:880 → 1097
      M_domain; M domain of GW182
      pfam16608
      Location:1098 → 1350
      TNRC6-PABC_bdg; TNRC6-PABC binding domain

    2. XM_009302365.4 → XP_009300640.2  trinucleotide repeat-containing gene 6C protein isoform X1

      UniProtKB/TrEMBL
      A0A8M3ATC8
      Conserved Domains (4) summary
      cd12713
      Location:1388 → 1470
      RRM_TNRC6C; RNA recognition motif in vertebrate trinucleotide repeat-containing gene 6C protein (TNRC6C)
      cd14283
      Location:800 → 837
      UBA_TNR6C; UBA domain found in trinucleotide repeat-containing gene 6C protein (TNRC6C) and similar proteins
      pfam12938
      Location:880 → 1097
      M_domain; M domain of GW182
      pfam16608
      Location:1098 → 1387
      TNRC6-PABC_bdg; TNRC6-PABC binding domain

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395252.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      448475..514557 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021474088.2 → XP_021329763.1  trinucleotide repeat-containing gene 6C protein isoform X2

      UniProtKB/TrEMBL
      A0A0R4IVQ1, A0A8M9PMP3
      Conserved Domains (4) summary
      cd12713
      Location:1351 → 1433
      RRM_TNRC6C; RNA recognition motif in vertebrate trinucleotide repeat-containing gene 6C protein (TNRC6C)
      cd14283
      Location:800 → 837
      UBA_TNR6C; UBA domain found in trinucleotide repeat-containing gene 6C protein (TNRC6C) and similar proteins
      pfam12938
      Location:880 → 1097
      M_domain; M domain of GW182
      pfam16608
      Location:1098 → 1350
      TNRC6-PABC_bdg; TNRC6-PABC binding domain

    2. XM_021474086.2 → XP_021329761.1  trinucleotide repeat-containing gene 6C protein isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q4I3
      Conserved Domains (4) summary
      cd12713
      Location:1388 → 1470
      RRM_TNRC6C; RNA recognition motif in vertebrate trinucleotide repeat-containing gene 6C protein (TNRC6C)
      cd14283
      Location:800 → 837
      UBA_TNR6C; UBA domain found in trinucleotide repeat-containing gene 6C protein (TNRC6C) and similar proteins
      pfam12938
      Location:880 → 1097
      M_domain; M domain of GW182
      pfam16608
      Location:1098 → 1387
      TNRC6-PABC_bdg; TNRC6-PABC binding domain
    Nucleotide Protein Strain
    Heading Accession and Version

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