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    tspan18a tetraspanin 18a [ Danio rerio (zebrafish) ]

    Gene ID: 437007, updated on 4-Jan-2025

    Summary

    Official Symbol
    tspan18aprovided by ZNC
    Official Full Name
    tetraspanin 18aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-232
    See related
    Ensembl:ENSDARG00000056656 AllianceGenome:ZFIN:ZDB-GENE-040718-232
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tspan18; zgc:101106
    Summary
    Acts upstream of or within artery development; regulation of sprouting angiogenesis; and venous blood vessel development. Predicted to be located in membrane. Is expressed in dorsal aorta; intersegmental vessel; posterior cardinal vein; trunk vasculature; and yolk. Orthologous to human TSPAN18 (tetraspanin 18). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See tspan18a in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (26756091..26837182)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (26491760..26565987)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene tumor protein p53 inducible protein 11a Neighboring gene CD82 molecule a Neighboring gene uncharacterized LOC137496170 Neighboring gene si:ch211-107p11.3 Neighboring gene exostosin glycosyltransferase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    tetraspanin-18a
    Names
    tetraspanin 18

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002734.3NP_001002734.2  tetraspanin-18a isoform 1

      Status: VALIDATED

      Source sequence(s)
      BX510305, CR394555
      UniProtKB/TrEMBL
      A0A8M2BK40, A0A8M9QBT2, F1QI47
      Related
      ENSDARP00000114616.1, ENSDART00000134717.3
    2. NM_001430973.1NP_001417902.1  tetraspanin-18a isoform 2

      Status: VALIDATED

      Source sequence(s)
      BX510305, CR394555
      UniProtKB/TrEMBL
      A0A8M2BJK7, A0A8M9QBT2, Q6DGC4
      Related
      ENSDARP00000131977.1, ENSDART00000167956.3

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      26756091..26837182
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068222223.1XP_068078324.1  tetraspanin-18a isoform X1

      UniProtKB/TrEMBL
      A0A8M9QBT2
    2. XM_021477463.2XP_021333138.1  tetraspanin-18a isoform X3

      UniProtKB/TrEMBL
      A0A8M2BJK7, A0A8M9QBT2, Q6DGC4
      Conserved Domains (1) summary
      pfam00335
      Location:9238
      Tetraspannin; Tetraspanin family
    3. XM_068222222.1XP_068078323.1  tetraspanin-18a isoform X1

      UniProtKB/TrEMBL
      A0A8M9QBT2
    4. XM_009303047.4XP_009301322.1  tetraspanin-18a isoform X2

      See identical proteins and their annotated locations for XP_009301322.1

      UniProtKB/TrEMBL
      A0A8M2BK40, A0A8M9QBT2, F1QI47
      Conserved Domains (1) summary
      pfam00335
      Location:21250
      Tetraspannin; Tetraspanin family
    5. XM_009303049.4XP_009301324.1  tetraspanin-18a isoform X3

      See identical proteins and their annotated locations for XP_009301324.1

      UniProtKB/TrEMBL
      A0A8M2BJK7, A0A8M9QBT2, Q6DGC4
      Conserved Domains (1) summary
      pfam00335
      Location:9238
      Tetraspannin; Tetraspanin family
    6. XM_068222221.1XP_068078322.1  tetraspanin-18a isoform X1

      UniProtKB/TrEMBL
      A0A8M9QBT2
    7. XM_068222224.1XP_068078325.1  tetraspanin-18a isoform X3

      UniProtKB/TrEMBL
      A0A8M2BJK7, A0A8M9QBT2, Q6DGC4
    8. XM_005172273.5XP_005172330.1  tetraspanin-18a isoform X3

      See identical proteins and their annotated locations for XP_005172330.1

      UniProtKB/TrEMBL
      A0A8M2BJK7, A0A8M9QBT2, Q6DGC4
      Related
      ENSDARP00000149840.1, ENSDART00000186464.1
      Conserved Domains (1) summary
      pfam00335
      Location:9238
      Tetraspannin; Tetraspanin family
    9. XM_068222218.1XP_068078319.1  tetraspanin-18a isoform X1

      UniProtKB/TrEMBL
      A0A8M9QBT2
    10. XM_068222219.1XP_068078320.1  tetraspanin-18a isoform X2

      UniProtKB/TrEMBL
      A0A8M2BK40, A0A8M9QBT2, F1QI47
    11. XM_068222220.1XP_068078321.1  tetraspanin-18a isoform X3

      UniProtKB/TrEMBL
      A0A8M2BJK7, A0A8M9QBT2, Q6DGC4