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    CISH cytokine inducible SH2 containing protein [ Numida meleagris (helmeted guineafowl) ]

    Gene ID: 110404944, updated on 15-Mar-2024

    Summary

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    Gene symbol
    CISH
    Gene description
    cytokine inducible SH2 containing protein
    See related
    Ensembl:ENSNMEG00000008933
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Numida meleagris
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
    Orthologs
    human mouse all
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    Genomic context

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    See CISH in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    100 current NumMel1.0 (GCF_002078875.1) 11 NC_034419.1 (1715396..1722028, complement)

    Chromosome 11 - NC_034419.1Genomic Context describing neighboring genes Neighboring gene high mobility group protein HMGI-C-like Neighboring gene chromosome 11 C3orf18 homolog Neighboring gene HemK methyltransferase family member 1 Neighboring gene MAPK activated protein kinase 3 Neighboring gene uncharacterized LOC110404682

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_034419.1 Chromosome 11 Reference NumMel1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of phosphatidylinositol 3-kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytokine-inducible SH2-containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NumMel1.0 Primary Assembly

    Genomic

    1. NC_034419.1 Reference NumMel1.0 Primary Assembly

      Range
      1715396..1722028 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021409734.1 → XP_021265409.1  cytokine-inducible SH2-containing protein

      Related
      ENSNMEP00000009212.1, ENSNMET00000014745.1
      Conserved Domains (2) summary
      cd10718
      Location:88 → 175
      SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)
      cd03734
      Location:218 → 258
      SOCS_CIS1; SOCS (suppressors of cytokine signaling) box of CIS (cytokine-inducible SH2 protein) 1-like proteins. Together with the SOCS proteins, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. ...
    Nucleotide Protein
    Heading Accession and Version

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