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    UBP25 ubiquitin-specific protease 25 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820662, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UBP25
    Official Full Name
    ubiquitin-specific protease 25
    Primary source
    TAIR:AT3G14400
    Locus tag
    AT3G14400
    See related
    Araport:AT3G14400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ubiquitin-specific protease 25; UBIQUITIN-SPECIFIC PROTEASE 25
    Summary
    Encodes a ubiquitin-specific protease.
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    Genomic context

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    See UBP25 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (4811486..4815515, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Pyridoxal-dependent decarboxylase family protein Neighboring gene uncharacterized protein Neighboring gene Nucleotide/sugar transporter family protein Neighboring gene Aldolase-type TIM barrel family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lipid-mediated activation of plasma membrane-localized deubiquitylating enzymes modulate endosomal trafficking. Vogel K, et al. Nat Commun, 2022 Nov 12. PMID 36371501, Free PMC Article
    2. VH1/BRL2 receptor-like kinase interacts with vascular-specific adaptor proteins VIT and VIK to influence leaf venation. Ceserani T, et al. Plant J, 2009 Mar. PMID 19000166, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_112299.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-specific protease 25
    NP_566486.1
    • ubiquitin-specific protease 25 (UBP25); FUNCTIONS IN: ubiquitin-specific protease activity, ubiquitin thiolesterase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 23 (TAIR:AT5G57990.1); Has 8659 Blast hits to 7314 proteins in 254 species: Archae - 0; Bacteria - 9; Metazoa - 4447; Fungi - 1449; Plants - 1041; Viruses - 9; Other Eukaryotes - 1704 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4811486..4815515 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112299.4 → NP_566486.1  ubiquitin-specific protease 25 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566486.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VZF5, Q9FPS2, Q9LUK9
      UniProtKB/TrEMBL
      A0A178VGL4, A0A654F8F7
      Conserved Domains (2) summary
      cd02661
      Location:23 → 333
      Peptidase_C19E; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam10163
      Location:576 → 652
      EnY2; Transcription factor e(y)2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FPS2.1

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