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    F09E5.11 Transmembrane protein 199 [ Caenorhabditis elegans ]

    Gene ID: 184242, updated on 9-Dec-2024

    Summary

    Official Symbol
    F09E5.11
    Official Full Name
    Transmembrane protein 199
    Primary source
    WormBase:WBGene00017289
    Locus tag
    CELE_F09E5.11
    See related
    AllianceGenome:WB:WBGene00017289
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in vacuolar proton-transporting V-type ATPase complex assembly. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endomembrane system. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIp. Orthologous to human TMEM199 (transmembrane protein 199). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See F09E5.11 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (5357308..5358187, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Pyridoxal phosphate homeostasis protein Neighboring gene PI31_Prot_N domain-containing protein Neighboring gene Serpentine receptor class gamma-69 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Boca/MESD chaperone for YWTD beta-propeller-EGF

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in vacuolar proton-transporting V-type ATPase complex assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Transmembrane protein 199
    NP_495004.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5357308..5358187 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062603.3NP_495004.2  Transmembrane protein 199 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495004.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19259
      Conserved Domains (1) summary
      pfam11712
      Location:79196
      Vma12; Endoplasmic reticulum-based factor for assembly of V-ATPase