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    rpusd1 RNA pseudouridine synthase domain containing 1 [ Danio rerio (zebrafish) ]

    Gene ID: 767786, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rpusd1provided by ZNC
    Official Full Name
    RNA pseudouridine synthase domain containing 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-444
    See related
    Ensembl:ENSDARG00000060192 AllianceGenome:ZFIN:ZDB-GENE-060929-444
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fe26f08; wu:fe26f08; zgc:153465
    Summary
    Predicted to enable pseudouridine synthase activity. Predicted to be involved in enzyme-directed rRNA pseudouridine synthesis. Predicted to act upstream of or within pseudouridine synthesis. Orthologous to human RPUSD1 (RNA pseudouridine synthase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rpusd1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (35542044..35550978)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (35412541..35420637)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene trinucleotide repeat containing adaptor 6A Neighboring gene NADH:ubiquinone oxidoreductase subunit AB1b Neighboring gene dynactin 5 Neighboring gene guanine nucleotide binding protein (G protein), gamma 13b Neighboring gene TNF receptor-associated factor 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC153465

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pseudouridine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA modification IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in enzyme-directed rRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RNA pseudouridylate synthase domain-containing protein 1
    Names
    RNA pseudouridylate synthase domain containing 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076753.1 → NP_001070221.1  RNA pseudouridylate synthase domain-containing protein 1

      See identical proteins and their annotated locations for NP_001070221.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124362
      UniProtKB/Swiss-Prot
      Q08C69
      Related
      ENSDARP00000113540.1, ENSDART00000146529.3
      Conserved Domains (2) summary
      cd02869
      Location:18 → 213
      PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
      COG0564
      Location:9 → 228
      RluA; Pseudouridylate synthase, 23S rRNA- or tRNA-specific [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      35542044..35550978
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068217651.1 → XP_068073752.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M6YZ42, F1RAY7
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08C69.1 GenPept UniProtKB/Swiss-Prot:Q08C69

    Gene LinkOut

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