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    Ptges2 prostaglandin E synthase 2 [ Castor canadensis (American beaver) ]

    Gene ID: 109686775, updated on 14-Mar-2024

    Summary

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    Gene symbol
    Ptges2
    Gene description
    prostaglandin E synthase 2
    See related
    Ensembl:ENSCCNG00000027431
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Castor canadensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
    Orthologs
    human mouse all
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    Genomic context

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    See Ptges2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017870528.1 (356460..361551, complement)

    NW_017870528.1Genomic Context describing neighboring genes Neighboring gene nuclear apoptosis inducing factor 1 Neighboring gene solute carrier family 25 member 25 Neighboring gene lipocalin 2 Neighboring gene bublin coiled coil protein Neighboring gene CDKN1A interacting zinc finger protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_017870528.1 Unplaced Scaffold Reference C.can genome v1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. De Novo Genome and Transcriptome Assembly of the Canadian Beaver (Castor canadensis). Lok S, et al. G3 (Bethesda), 2017 Feb 9. PMID 28087693, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables prostaglandin-E synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prostaglandin E synthase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference C.can genome v1.0

    Genomic

    1. NW_017870528.1 Reference C.can genome v1.0

      Range
      356460..361551 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_020164255.1 → XP_020019844.1  prostaglandin E synthase 2 isoform X2

      UniProtKB/TrEMBL
      A0A250YGX3, A0A8B7ULQ2
      Conserved Domains (2) summary
      cd03197
      Location:227 → 358
      GST_C_mPGES2; C-terminal, alpha helical domain of microsomal Prostaglandin E synthase Type 2
      cd03040
      Location:104 → 180
      GST_N_mPGES2; GST_N family; microsomal Prostaglandin E synthase Type 2 (mPGES2) subfamily; mPGES2 is a membrane-anchored dimeric protein containing a CXXC motif which catalyzes the isomerization of PGH2 to PGE2. Unlike cytosolic PGE synthase (cPGES) and microsomal ...

    2. XM_020164254.1 → XP_020019843.1  prostaglandin E synthase 2 isoform X1

      UniProtKB/TrEMBL
      A0A250YGX3, A0A8B7UJU7
      Related
      ENSCCNP00000028485.1, ENSCCNT00000035974.1
      Conserved Domains (2) summary
      cd03197
      Location:227 → 375
      GST_C_mPGES2; C-terminal, alpha helical domain of microsomal Prostaglandin E synthase Type 2
      cd03040
      Location:104 → 180
      GST_N_mPGES2; GST_N family; microsomal Prostaglandin E synthase Type 2 (mPGES2) subfamily; mPGES2 is a membrane-anchored dimeric protein containing a CXXC motif which catalyzes the isomerization of PGH2 to PGE2. Unlike cytosolic PGE synthase (cPGES) and microsomal ...
    Nucleotide Protein
    Heading Accession and Version

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