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    N6AMT1 N-6 adenine-specific DNA methyltransferase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706937, updated on 5-Mar-2024

    Summary

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    Gene symbol
    N6AMT1
    Gene description
    N-6 adenine-specific DNA methyltransferase 1
    Locus tag
    EGK_13342
    See related
    Ensembl:ENSMMUG00000061034
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See N6AMT1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (17793070..17810395)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (18004004..18021337)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114676828 Neighboring gene THUMP domain-containing protein 1-like Neighboring gene 60 kDa heat shock protein, mitochondrial pseudogene Neighboring gene uncharacterized LOC106997288 Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L7a pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of eRF1 methyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methyltransferase N6AMT1
    Names
    HemK methyltransferase family member 2
    N-6 adenine-specific DNA methyltransferase 1 (putative)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      17793070..17810395
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002803158.3 → XP_002803204.1  methyltransferase N6AMT1 isoform X2

      See identical proteins and their annotated locations for XP_002803204.1

      UniProtKB/TrEMBL
      H9YYR4
      Conserved Domains (1) summary
      cl17173
      Location:21 → 185
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    2. XM_001103046.4 → XP_001103046.1  methyltransferase N6AMT1 isoform X1

      See identical proteins and their annotated locations for XP_001103046.1

      UniProtKB/TrEMBL
      A0A5F7ZGA8, A0A8J8YK96, G7MN56, H9YYR4
      Related
      ENSMMUP00000063663.1, ENSMMUT00000089782.1
      Conserved Domains (2) summary
      COG2890
      Location:20 → 190
      HemK; Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]
      cl17173
      Location:21 → 213
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    RNA

    1. XR_001443431.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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