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    ROPGEF3 RHO guanyl-nucleotide exchange factor 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827967, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ROPGEF3
    Official Full Name
    RHO guanyl-nucleotide exchange factor 3
    Primary source
    TAIR:AT4G00460
    Locus tag
    AT4G00460
    See related
    Araport:AT4G00460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATROPGEF3; A_IG005I10.1; A_IG005I10_1; KINASE PARTNER PROTEIN-LIKE; KPP-LIKE; RHO guanyl-nucleotide exchange factor 3; ROP (rho of plants) guanine nucleotide exchange factor 3
    Summary
    Encodes a member of KPP-like gene family, homolog of KPP (kinase partner protein) gene in tomato. Also a member of the RopGEF (guanine nucleotide exchange factor) family, containing the novel PRONE domain (plant-specific Rop nucleotide exchanger), which is exclusively active towards members of the Rop subfamily.
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    Genomic context

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    See ROPGEF3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Sequence:
    Chromosome: 4; NC_003075.7 (211000..213697, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene GPI-anchored adhesin-like protein, putative (DUF3741) Neighboring gene miscRNA Neighboring gene RNA polymerase II transcription mediator Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth. Gu Y, et al. Plant Cell, 2006 Feb. PMID 16415208, Free PMC Article
    2. A new family of RhoGEFs activates the Rop molecular switch in plants. Berken A, et al. Nature, 2005 Aug 25. PMID 15980860
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001125431.2
    NM_001340252.1
    NM_001340253.1
    NM_116271.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RHO guanyl-nucleotide exchange factor 3
    NP_001118903.1
    • RHO guanyl-nucleotide exchange factor 3 (ROPGEF3); CONTAINS InterPro DOMAIN/s: Rop nucleotide exchanger, PRONE (InterPro:IPR005512); BEST Arabidopsis thaliana protein match is: RHO guanyl-nucleotide exchange factor 2 (TAIR:AT1G01700.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_191956.2
    • RHO guanyl-nucleotide exchange factor 3 (ROPGEF3); CONTAINS InterPro DOMAIN/s: Rop nucleotide exchanger, PRONE (InterPro:IPR005512); BEST Arabidopsis thaliana protein match is: RHO guanyl-nucleotide exchange factor 2 (TAIR:AT1G01700.1); Has 292 Blast hits to 291 proteins in 14 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 292; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      211000..213697 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001125431.2 → NP_001118903.1  RHO guanyl-nucleotide exchange factor 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001118903.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4IJ27, O23056, O65256, Q9M163
      UniProtKB/TrEMBL
      A0A178V0U5, A0A5S9XNM3, A0A654FKL6
      Conserved Domains (1) summary
      pfam03759
      Location:104 → 470
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)

    2. NM_116271.3 → NP_191956.2  RHO guanyl-nucleotide exchange factor 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191956.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H471
      Conserved Domains (1) summary
      pfam03759
      Location:104 → 319
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)

    3. NM_001340253.1 → NP_001328183.1  RHO guanyl-nucleotide exchange factor 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4IJ27, O23056, O65256, Q9M163
      UniProtKB/TrEMBL
      A0A178V0U5, A0A5S9XNM3, A0A654FKL6
      Conserved Domains (1) summary
      pfam03759
      Location:104 → 470
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)

    4. NM_001340252.1 → NP_001328184.1  RHO guanyl-nucleotide exchange factor 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B3X4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A4IJ27.1

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